<SEC-DOCUMENT>0001628280-25-039623-index.html : 20250811
<SEC-HEADER>0001628280-25-039623.hdr.sgml : 20250811
<ACCEPTANCE-DATETIME>20250811164806
ACCESSION NUMBER:		0001628280-25-039623
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20250811
DATE AS OF CHANGE:		20250811

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Neurogene Inc.
		CENTRAL INDEX KEY:			0001404644
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				980542593
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-286057
		FILM NUMBER:		251202679

	BUSINESS ADDRESS:	
		STREET 1:		535 W 24TH STREET
		STREET 2:		5TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10011
		BUSINESS PHONE:		(877) 237-5020

	MAIL ADDRESS:	
		STREET 1:		535 W 24TH STREET
		STREET 2:		5TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10011

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Neoleukin Therapeutics, Inc.
		DATE OF NAME CHANGE:	20190812

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AQUINOX PHARMACEUTICALS, INC
		DATE OF NAME CHANGE:	20140128

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AQUINOX PHARMACEUTICALS (USA) INC
		DATE OF NAME CHANGE:	20070626
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>ngne-2025atmprospectussupp.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: ngne-2025atmprospectussupp.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>neurogene.jpg
<TEXT>
Document 2 - file: neurogene.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>prospectusa.jpg
<TEXT>
Document 3 - file: prospectusa.jpg

</DOCUMENT>
</SEC-DOCUMENT>