    <SEC-DOCUMENT>0001404644-25-000070-index.html : 20250630
    <SEC-HEADER>0001404644-25-000070.hdr.sgml : 20250630
    <ACCEPTANCE-DATETIME>20250630160207
    ACCESSION NUMBER:		0001404644-25-000070
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		50
    CONFORMED PERIOD OF REPORT:	20250630
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20250630
    DATE AS OF CHANGE:		20250630

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Neurogene Inc.
    		CENTRAL INDEX KEY:			0001404644
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				980542593
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36327
    		FILM NUMBER:		251091905

    	BUSINESS ADDRESS:
    		STREET 1:		535 W 24TH STREET
    		STREET 2:		5TH FLOOR
    		CITY:			NEW YORK
    		STATE:			NY
    		ZIP:			10011
    		BUSINESS PHONE:		(877) 237-5020

    	MAIL ADDRESS:
    		STREET 1:		535 W 24TH STREET
    		STREET 2:		5TH FLOOR
    		CITY:			NEW YORK
    		STATE:			NY
    		ZIP:			10011

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Neoleukin Therapeutics, Inc.
    		DATE OF NAME CHANGE:	20190812

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AQUINOX PHARMACEUTICALS, INC
    		DATE OF NAME CHANGE:	20140128

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AQUINOX PHARMACEUTICALS (USA) INC
    		DATE OF NAME CHANGE:	20070626
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>ngne-20250630.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: ngne-20250630.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>regupdaterelease.htm
    <DESCRIPTION>EX-99.1
    <TEXT>
    Document 2 - file: regupdaterelease.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.2
    <SEQUENCE>3
    <FILENAME>a202506_ngnecorporatepre.htm
    <DESCRIPTION>EX-99.2
    <TEXT>
    Document 3 - file: a202506_ngnecorporatepre.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.SCH
    <SEQUENCE>4
    <FILENAME>ngne-20250630.xsd
    <DESCRIPTION>XBRL TAXONOMY EXTENSION SCHEMA DOCUMENT
    <TEXT>
    Document 4 - file: ngne-20250630.xsd

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.LAB
    <SEQUENCE>5
    <FILENAME>ngne-20250630_lab.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION LABEL LINKBASE DOCUMENT
    <TEXT>
    Document 5 - file: ngne-20250630_lab.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-101.PRE
    <SEQUENCE>6
    <FILENAME>ngne-20250630_pre.xml
    <DESCRIPTION>XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE DOCUMENT
    <TEXT>
    Document 6 - file: ngne-20250630_pre.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>a202506_ngnecorporatepre001.jpg
    <TEXT>
    Document 7 - file: a202506_ngnecorporatepre001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>a202506_ngnecorporatepre002.jpg
    <TEXT>
    Document 8 - file: a202506_ngnecorporatepre002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>a202506_ngnecorporatepre003.jpg
    <TEXT>
    Document 9 - file: a202506_ngnecorporatepre003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>a202506_ngnecorporatepre004.jpg
    <TEXT>
    Document 10 - file: a202506_ngnecorporatepre004.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>a202506_ngnecorporatepre005.jpg
    <TEXT>
    Document 11 - file: a202506_ngnecorporatepre005.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>a202506_ngnecorporatepre006.jpg
    <TEXT>
    Document 12 - file: a202506_ngnecorporatepre006.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>a202506_ngnecorporatepre007.jpg
    <TEXT>
    Document 13 - file: a202506_ngnecorporatepre007.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>a202506_ngnecorporatepre008.jpg
    <TEXT>
    Document 14 - file: a202506_ngnecorporatepre008.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>a202506_ngnecorporatepre009.jpg
    <TEXT>
    Document 15 - file: a202506_ngnecorporatepre009.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>a202506_ngnecorporatepre010.jpg
    <TEXT>
    Document 16 - file: a202506_ngnecorporatepre010.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>a202506_ngnecorporatepre011.jpg
    <TEXT>
    Document 17 - file: a202506_ngnecorporatepre011.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>a202506_ngnecorporatepre012.jpg
    <TEXT>
    Document 18 - file: a202506_ngnecorporatepre012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>a202506_ngnecorporatepre013.jpg
    <TEXT>
    Document 19 - file: a202506_ngnecorporatepre013.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>a202506_ngnecorporatepre014.jpg
    <TEXT>
    Document 20 - file: a202506_ngnecorporatepre014.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>a202506_ngnecorporatepre015.jpg
    <TEXT>
    Document 21 - file: a202506_ngnecorporatepre015.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>a202506_ngnecorporatepre016.jpg
    <TEXT>
    Document 22 - file: a202506_ngnecorporatepre016.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>a202506_ngnecorporatepre017.jpg
    <TEXT>
    Document 23 - file: a202506_ngnecorporatepre017.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>a202506_ngnecorporatepre018.jpg
    <TEXT>
    Document 24 - file: a202506_ngnecorporatepre018.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>a202506_ngnecorporatepre019.jpg
    <TEXT>
    Document 25 - file: a202506_ngnecorporatepre019.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>a202506_ngnecorporatepre020.jpg
    <TEXT>
    Document 26 - file: a202506_ngnecorporatepre020.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>a202506_ngnecorporatepre021.jpg
    <TEXT>
    Document 27 - file: a202506_ngnecorporatepre021.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>a202506_ngnecorporatepre022.jpg
    <TEXT>
    Document 28 - file: a202506_ngnecorporatepre022.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>a202506_ngnecorporatepre023.jpg
    <TEXT>
    Document 29 - file: a202506_ngnecorporatepre023.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>a202506_ngnecorporatepre024.jpg
    <TEXT>
    Document 30 - file: a202506_ngnecorporatepre024.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>a202506_ngnecorporatepre025.jpg
    <TEXT>
    Document 31 - file: a202506_ngnecorporatepre025.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>a202506_ngnecorporatepre026.jpg
    <TEXT>
    Document 32 - file: a202506_ngnecorporatepre026.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>33
    <FILENAME>a202506_ngnecorporatepre027.jpg
    <TEXT>
    Document 33 - file: a202506_ngnecorporatepre027.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>34
    <FILENAME>a202506_ngnecorporatepre028.jpg
    <TEXT>
    Document 34 - file: a202506_ngnecorporatepre028.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>35
    <FILENAME>a202506_ngnecorporatepre029.jpg
    <TEXT>
    Document 35 - file: a202506_ngnecorporatepre029.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>36
    <FILENAME>a202506_ngnecorporatepre030.jpg
    <TEXT>
    Document 36 - file: a202506_ngnecorporatepre030.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>37
    <FILENAME>a202506_ngnecorporatepre031.jpg
    <TEXT>
    Document 37 - file: a202506_ngnecorporatepre031.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>38
    <FILENAME>a202506_ngnecorporatepre032.jpg
    <TEXT>
    Document 38 - file: a202506_ngnecorporatepre032.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>39
    <FILENAME>a202506_ngnecorporatepre033.jpg
    <TEXT>
    Document 39 - file: a202506_ngnecorporatepre033.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>40
    <FILENAME>a202506_ngnecorporatepre034.jpg
    <TEXT>
    Document 40 - file: a202506_ngnecorporatepre034.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>41
    <FILENAME>a202506_ngnecorporatepre035.jpg
    <TEXT>
    Document 41 - file: a202506_ngnecorporatepre035.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>42
    <FILENAME>image_0a.jpg
    <TEXT>
    Document 42 - file: image_0a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>44
    <FILENAME>R1.htm
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 44 - file: R1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>45
    <FILENAME>Show.js
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 45 - file: Show.js

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>46
    <FILENAME>report.css
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 46 - file: report.css

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>48
    <FILENAME>FilingSummary.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 48 - file: FilingSummary.html

    Document 48 - RAW XML: FilingSummary.xml

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>JSON
    <SEQUENCE>50
    <FILENAME>MetaLinks.json
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 50 - file: MetaLinks.json

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>ZIP
    <SEQUENCE>51
    <FILENAME>0001404644-25-000070-xbrl.zip
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 51 - file: 0001404644-25-000070-xbrl.zip

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>XML
    <SEQUENCE>52
    <FILENAME>ngne-20250630_htm.xml
    <DESCRIPTION>IDEA: XBRL DOCUMENT
    <TEXT>
    Document 52 - file: ngne-20250630_htm.html

    Document 52 - RAW XML: ngne-20250630_htm.xml

    </DOCUMENT>
    </SEC-DOCUMENT>