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Operating Expenses - Summary of Research and Development (Detail) - EUR (€) € in Thousands | 12 Months Ended
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Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Disclosure of Other Operating Expense [Abstract] |  |  |
Personnel expenses | € 37,112 | € 32,777 | € 13,268
Sub-contracting,collaboration, and consultants | 54,397 | 34,413 | 15,325
Research supplies | 1,464 | 1,234 | 911
Rental | 2,018 | 1,903 | 1,094
Conferences, travel expenses | 2,807 | 2,387 | 1,233
Depreciation and amortization | 2,424 | 1,141 | 1,000
Small equipments and other supplies | 2,646 | 2,675 | 795
Others | 2,364 | 2,298 | 608
Total research and development expenses | € 105,232 | € 78,828 | € 34,234

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