<SEC-DOCUMENT>0001104659-23-021719.txt : 20230214
<SEC-HEADER>0001104659-23-021719.hdr.sgml : 20230214
<ACCEPTANCE-DATETIME>20230214163158
ACCESSION NUMBER:		0001104659-23-021719
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230214
DATE AS OF CHANGE:		20230214
GROUP MEMBERS:		KOH, BONG
GROUP MEMBERS:		SHAH, NIMISH
GROUP MEMBERS:		VENROCK HEALTHCARE CAPITAL PARTNERS EG, L.P.
GROUP MEMBERS:		VENROCK HEALTHCARE CAPITAL PARTNERS III, L.P.
GROUP MEMBERS:		VHCP CO-INVESTMENT HOLDINGS II, LLC
GROUP MEMBERS:		VHCP CO-INVESTMENT HOLDINGS III, LLC
GROUP MEMBERS:		VHCP MANAGEMENT EG, LLC
GROUP MEMBERS:		VHCP MANAGEMENT II, LLC
GROUP MEMBERS:		VHCP MANAGEMENT III, LLC

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			DBV Technologies S.A.
		CENTRAL INDEX KEY:			0001613780
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			I0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88701
		FILM NUMBER:		23630256

	BUSINESS ADDRESS:	
		STREET 1:		177-181 AVENUE PIERRE BROSSOLETTE
		CITY:			MONTROUGE
		STATE:			I0
		ZIP:			92120
		BUSINESS PHONE:		33(0)155427878

	MAIL ADDRESS:	
		STREET 1:		177-181 AVENUE PIERRE BROSSOLETTE
		CITY:			MONTROUGE
		STATE:			I0
		ZIP:			92120

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Venrock Healthcare Capital Partners II, L.P.
		CENTRAL INDEX KEY:			0001602264
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
		BUSINESS PHONE:		650 475 3734

	MAIL ADDRESS:	
		STREET 1:		7 BRYANT PARK
		STREET 2:		23RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>tm236635d6_sc13ga.htm
<DESCRIPTION>SC 13G/A
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
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<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 0; margin-bottom: 0; width: 100%"><DIV STYLE="border-top: Black 2pt solid; font-size: 1pt; border-bottom: Black 1pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES</B></P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>WASHINGTON, D.C. 20549</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 18pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SCHEDULE 13G/A</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNDER THE SECURITIES EXCHANGE ACT OF 1934<BR>
(Amendment No. 1)*</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;&nbsp;</P>

<P STYLE="font: 24pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>DBV Technologies S.A.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Name of Issuer)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Ordinary Shares, &#8364;0.10 nominal value
per share</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Title of Class of Securities)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>23306J101 (American Depositary Shares, each
representing one-half of one Ordinary Share)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(CUSIP Number)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>December 31, 2022</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Date of Event Which Requires Filing of This
Statement)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the appropriate box to designate the rule pursuant to which
this Schedule is filed:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%; font-size: 10pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%; font-size: 10pt"><FONT STYLE="font-family: Wingdings; font-size: 10pt">&uml;</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%; font-size: 10pt"><FONT STYLE="font-size: 10pt">Rule 13d-1(b)</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-family: Wingdings; font-size: 10pt">x</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Rule 13d-1(c)</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-family: Wingdings; font-size: 10pt">&uml;</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Rule 13d-1(d)</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%"><FONT STYLE="font-size: 10pt">*</FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 98%"><FONT STYLE="font-size: 10pt">The remainder of this cover page shall be filled out for a
    reporting person&#8217;s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment
    containing information which would alter the disclosures provided in a prior cover page.</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">The information required in the remainder of this cover page shall
not be deemed to be &#8220;filed&#8221; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&#8220;Act&#8221;) or otherwise
subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 0; margin-bottom: 0; width: 100%"><DIV STYLE="border-top: Black 1pt solid; font-size: 1pt; border-bottom: Black 2pt solid">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 2 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt 2.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: bottom; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; vertical-align: bottom; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">1.
    </FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Venrock Healthcare Capital Partners II, L.P.</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a) <FONT STYLE="font-family: Wingdings">x</FONT><SUP>1</SUP>
    (b) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">5.
    </FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="padding: 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.25pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: bottom; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1.5pt solid; vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check if the Aggregate Amount in Row (9) Excludes Certain Shares
    (See Instructions) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">PN</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 4%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 6%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 83%">&nbsp;</TD></TR>
  </TABLE>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                                Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners
                                EG, L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and
                                Bong Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable
                                            upon the exercise of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;)
                                            held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares
                                            issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings II, LLC, (iii)
                                            2,093,431 shares and 23,293 shares issuable upon the exercise of Warrants held by Venrock
                                            Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330 shares issuable upon
                                            the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC and (v) 5,659,991 shares
                                            and 62,977 shares issuable upon the exercise of Warrants held by Venrock Healthcare Capital
                                            Partners EG, L.P. The share numbers in the preceding sentence represent the maximum number
                                            of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                            a result of the beneficial ownership provision described in the following sentence. Under
                                            the terms of the Warrants, the Issuer may not effect the exercise of any such Warrant, and
                                            a holder will not be entitled to exercise any portion of such Warrant, if, upon giving effect
                                            to such exercise, the aggregate number of ordinary shares beneficially owned by the holder
                                            (together with its affiliates and other attribution parties) would exceed 9.99% of the number
                                            of ordinary shares outstanding immediately after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                                obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                                Warrants described in Footnote 2 above.</TD></TR></TABLE>

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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 3 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt 2.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: bottom; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; vertical-align: bottom; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">1.
    </FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Co-Investment Holdings II, LLC</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a) <FONT STYLE="font-family: Wingdings">x</FONT><SUP>1</SUP>
    (b) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">5.
    </FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="padding: 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.25pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: bottom; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1.5pt solid; vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check if the Aggregate Amount in Row (9) Excludes Certain Shares
    (See Instructions) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">OO</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 4%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 6%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 83%">&nbsp;</TD></TR>
  </TABLE>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                                Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners
                                EG, L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and
                                Bong Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable
                                            upon the exercise of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;)
                                            held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares
                                            issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings II, LLC, (iii)
                                            2,093,431 shares and 23,293 shares issuable upon the exercise of Warrants held by Venrock
                                            Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330 shares issuable upon
                                            the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC and (v) 5,659,991 shares
                                            and 62,977 shares issuable upon the exercise of Warrants held by Venrock Healthcare Capital
                                            Partners EG, L.P. The share numbers in the preceding sentence represent the maximum number
                                            of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                            a result of the beneficial ownership provision described in the following sentence. Under
                                            the terms of the Warrants, the Issuer may not effect the exercise of any such Warrant, and
                                            a holder will not be entitled to exercise any portion of such Warrant, if, upon giving effect
                                            to such exercise, the aggregate number of ordinary shares beneficially owned by the holder
                                            (together with its affiliates and other attribution parties) would exceed 9.99% of the number
                                            of ordinary shares outstanding immediately after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

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    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 4 of 17</FONT></TD></TR>
  </TABLE>
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  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt 2.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: bottom; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; vertical-align: bottom; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">1.
    </FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Venrock Healthcare Capital Partners III, L.P.</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a) <FONT STYLE="font-family: Wingdings">x</FONT><SUP>1</SUP>
    (b) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">5.
    </FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="padding: 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.25pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD STYLE="border-top: black 1.5pt solid; vertical-align: bottom; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1.5pt solid; vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check if the Aggregate Amount in Row (9) Excludes Certain Shares
    (See Instructions) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">PN</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 4%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 6%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 83%">&nbsp;</TD></TR>
  </TABLE>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares
                                            and 10,586 shares issuable upon the exercise of immediately exercisable pre-funded warrants
                                            (&#8220;Warrants&#8221;) held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717
                                            shares and 4,292 shares issuable upon the exercise of Warrants held by VHCP Co-Investment
                                            Holdings II, LLC, (iii) 2,093,431 shares and 23,293 shares issuable upon the exercise of
                                            Warrants held by Venrock Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330
                                            shares issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC
                                            and (v) 5,659,991 shares and 62,977 shares issuable upon the exercise of Warrants held by
                                            Venrock Healthcare Capital Partners EG, L.P. The share numbers in the preceding sentence
                                            represent the maximum number of ordinary shares issuable upon exercise of the Warrants held
                                            by the Reporting Persons as a result of the beneficial ownership provision described in the
                                            following sentence. Under the terms of the Warrants, the Issuer may not effect the exercise
                                            of any such Warrant, and a holder will not be entitled to exercise any portion of such Warrant,
                                            if, upon giving effect to such exercise, the aggregate number of ordinary shares beneficially
                                            owned by the holder (together with its affiliates and other attribution parties) would exceed
                                            9.99% of the number of ordinary shares outstanding immediately after giving effect to the
                                            exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 5 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 2.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1. </FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Co-Investment Holdings III, LLC</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(a) </FONT><FONT STYLE="font-family: Wingdings">x</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><SUP>1</SUP>
    (b) </FONT><FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5. </FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-left: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; padding: 0.25pt 2.25pt 0.25pt 0.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-top: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Check if the
    Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) </FONT><FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">11.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">OO</P></TD></TR>
  <TR>
    <TD STYLE="width: 4%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 6%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 2%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 83%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 18pt; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable
                                            upon the exercise of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;)
                                            held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares
                                            issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings II, LLC, (iii)
                                            2,093,431 shares and 23,293 shares issuable upon the exercise of Warrants held by Venrock
                                            Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330 shares issuable upon
                                            the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC and (v) 5,659,991 shares
                                            and 62,977 shares issuable upon the exercise of Warrants held by Venrock Healthcare Capital
                                            Partners EG, L.P. The share numbers in the preceding sentence represent the maximum number
                                            of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                            a result of the beneficial ownership provision described in the following sentence. Under
                                            the terms of the Warrants, the Issuer may not effect the exercise of any such Warrant, and
                                            a holder will not be entitled to exercise any portion of such Warrant, if, upon giving effect
                                            to such exercise, the aggregate number of ordinary shares beneficially owned by the holder
                                            (together with its affiliates and other attribution parties) would exceed 9.99% of the number
                                            of ordinary shares outstanding immediately after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 6 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt 2.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; vertical-align: bottom; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">1.
    </FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Venrock Healthcare Capital Partners EG, L.P.</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a) <FONT STYLE="font-family: Wingdings">x</FONT><SUP>1</SUP>
    (b) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">5.
    </FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="padding: 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.25pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1.5pt solid; vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check if the Aggregate Amount in Row (9) Excludes Certain Shares
    (See Instructions) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">PN</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 4%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 6%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 83%">&nbsp;</TD></TR>
  </TABLE>
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<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable upon the exercise
                                   of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;) held by Venrock Healthcare
                                   Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares issuable upon the exercise of Warrants
                                   held by VHCP Co-Investment Holdings II, LLC, (iii) 2,093,431 shares and 23,293 shares issuable upon
                                   the exercise of Warrants held by Venrock Healthcare Capital Partners III, L.P., (iv) 209,422 shares
                                   and 2,330 shares issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC
                                   and (v) 5,659,991 shares and 62,977 shares issuable upon the exercise of Warrants held by Venrock
                                   Healthcare Capital Partners EG, L.P. The share numbers in the preceding sentence represent the maximum
                                   number of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                   a result of the beneficial ownership provision described in the following sentence. Under the terms
                                   of the Warrants, the Issuer may not effect the exercise of any such Warrant, and a holder will not
                                   be entitled to exercise any portion of such Warrant, if, upon giving effect to such exercise, the
                                   aggregate number of ordinary shares beneficially owned by the holder (together with its affiliates
                                   and other attribution parties) would exceed 9.99% of the number of ordinary shares outstanding immediately
                                   after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD>3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information obtained from the Issuer
          on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the Warrants described in Footnote 2 above.</TD></TR></TABLE>

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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 7 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 2.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1. </FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Management II, LLC</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(a) </FONT><FONT STYLE="font-family: Wingdings">x</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><SUP>1</SUP>
    (b) </FONT><FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5. </FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-left: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; padding: 0.25pt 2.25pt 0.25pt 0.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-top: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Check if the
    Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) </FONT><FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">11.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">OO</P></TD></TR>
  <TR>
    <TD STYLE="width: 4%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 6%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 2%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD>
    <TD STYLE="width: 83%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt"><FONT STYLE="font-size: 1pt">&nbsp;</FONT></TD></TR>
  </TABLE>

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<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable
                                            upon the exercise of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;)
                                            held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares
                                            issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings II, LLC, (iii)
                                            2,093,431 shares and 23,293 shares issuable upon the exercise of Warrants held by Venrock
                                            Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330 shares issuable upon
                                            the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC and (v) 5,659,991 shares
                                            and 62,977 shares issuable upon the exercise of Warrants held by Venrock Healthcare Capital
                                            Partners EG, L.P. The share numbers in the preceding sentence represent the maximum number
                                            of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                            a result of the beneficial ownership provision described in the following sentence. Under
                                            the terms of the Warrants, the Issuer may not effect the exercise of any such Warrant, and
                                            a holder will not be entitled to exercise any portion of such Warrant, if, upon giving effect
                                            to such exercise, the aggregate number of ordinary shares beneficially owned by the holder
                                            (together with its affiliates and other attribution parties) would exceed 9.99% of the number
                                            of ordinary shares outstanding immediately after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 8 of 17</FONT></TD></TR>
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    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 2.25pt">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-top: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">1. </FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Management III, LLC</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">2.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">(a) </FONT><FONT STYLE="font-family: Wingdings">x</FONT><FONT STYLE="font-family: Times New Roman, Times, Serif"><SUP>1</SUP>
    (b) </FONT><FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">3.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5. </FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="vertical-align: top; border-left: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 2.25pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="vertical-align: bottom; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="vertical-align: top; border-right: black 1.5pt solid; padding: 0.25pt 2.25pt 0.25pt 0.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-top: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding-top: 0.75pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.75pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">10.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-family: Times New Roman, Times, Serif">Check if the
    Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) </FONT><FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">11.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: top; border-left: black 1.5pt solid; border-bottom: black 1.5pt solid; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 9.75pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">12.</FONT></TD>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1.5pt solid; border-right: black 1.5pt solid; padding-top: 0.25pt; padding-right: 2.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; border-right: black 1.5pt solid">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">OO</P></TD></TR>
  <TR>
    <TD STYLE="width: 4%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 6%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 2%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 1%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD>
    <TD STYLE="width: 83%; padding-top: 0.25pt; padding-right: 0.25pt; padding-left: 0.25pt">&nbsp;</TD></TR>
  </TABLE>

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<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares
                                            and 10,586 shares issuable upon the exercise of immediately exercisable pre-funded warrants
                                            (&#8220;Warrants&#8221;) held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717
                                            shares and 4,292 shares issuable upon the exercise of Warrants held by VHCP Co-Investment
                                            Holdings II, LLC, (iii) 2,093,431 shares and 23,293 shares issuable upon the exercise of
                                            Warrants held by Venrock Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330
                                            shares issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC
                                            and (v) 5,659,991 shares and 62,977 shares issuable upon the exercise of Warrants held by
                                            Venrock Healthcare Capital Partners EG, L.P. The share numbers in the preceding sentence
                                            represent the maximum number of ordinary shares issuable upon exercise of the Warrants held
                                            by the Reporting Persons as a result of the beneficial ownership provision described in the
                                            following sentence. Under the terms of the Warrants, the Issuer may not effect the exercise
                                            of any such Warrant, and a holder will not be entitled to exercise any portion of such Warrant,
                                            if, upon giving effect to such exercise, the aggregate number of ordinary shares beneficially
                                            owned by the holder (together with its affiliates and other attribution parties) would exceed
                                            9.99% of the number of ordinary shares outstanding immediately after giving effect to the
                                            exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 9 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt 2.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-top: black 1.5pt solid; vertical-align: bottom; padding: 0.75pt 0.25pt 0.25pt">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">1.
    </FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of reporting persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Management EG, LLC</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a) <FONT STYLE="font-family: Wingdings">x</FONT><SUP>1</SUP>
    (b) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Delaware</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">5.
    </FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.25pt 0.25pt 0.75pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD COLSPAN="2" STYLE="padding: 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="border-right: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.25pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-top: black 1.5pt solid; vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check if the Aggregate Amount in Row (9) Excludes Certain Shares
    (See Instructions) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="7" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">OO</P></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt; width: 4%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 6%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 1%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; width: 83%">&nbsp;</TD></TR>
  </TABLE>
<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable
                                            upon the exercise of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;)
                                            held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares
                                            issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings II, LLC, (iii)
                                            2,093,431 shares and 23,293 shares issuable upon the exercise of Warrants held by Venrock
                                            Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330 shares issuable upon
                                            the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC and (v) 5,659,991 shares
                                            and 62,977 shares issuable upon the exercise of Warrants held by Venrock Healthcare Capital
                                            Partners EG, L.P. The share numbers in the preceding sentence represent the maximum number
                                            of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                            a result of the beneficial ownership provision described in the following sentence. Under
                                            the terms of the Warrants, the Issuer may not effect the exercise of any such Warrant, and
                                            a holder will not be entitled to exercise any portion of such Warrant, if, upon giving effect
                                            to such exercise, the aggregate number of ordinary shares beneficially owned by the holder
                                            (together with its affiliates and other attribution parties) would exceed 9.99% of the number
                                            of ordinary shares outstanding immediately after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 10 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt 2.25pt; width: 4%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt; vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt; width: 6%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt; width: 3%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt; vertical-align: bottom; width: 2%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt; width: 84%">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">1.
    </FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of Reporting Persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shah, Nimish</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a) <FONT STYLE="font-family: Wingdings">x</FONT><SUP>1</SUP>
    (b) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">United States</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">5.
    </FONT></TD>
    <TD STYLE="border-bottom: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD STYLE="border-bottom: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD STYLE="border-bottom: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; padding: 0.25pt 2.25pt 0.25pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.75pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.75pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-top: black 1.5pt solid; vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check if the Aggregate Amount in Row (9) Excludes Certain Shares
    (See Instructions) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">IN</P></TD></TR>
  </TABLE>
<P STYLE="margin-top: 0; margin-bottom: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable
                                            upon the exercise of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;)
                                            held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares
                                            issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings II, LLC, (iii)
                                            2,093,431 shares and 23,293 shares issuable upon the exercise of Warrants held by Venrock
                                            Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330 shares issuable upon
                                            the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC and (v) 5,659,991 shares
                                            and 62,977 shares issuable upon the exercise of Warrants held by Venrock Healthcare Capital
                                            Partners EG, L.P. The share numbers in the preceding sentence represent the maximum number
                                            of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                            a result of the beneficial ownership provision described in the following sentence. Under
                                            the terms of the Warrants, the Issuer may not effect the exercise of any such Warrant, and
                                            a holder will not be entitled to exercise any portion of such Warrant, if, upon giving effect
                                            to such exercise, the aggregate number of ordinary shares beneficially owned by the holder
                                            (together with its affiliates and other attribution parties) would exceed 9.99% of the number
                                            of ordinary shares outstanding immediately after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 11 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt 2.25pt; width: 4%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt; vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt; width: 6%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt; width: 3%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; padding: 0.75pt 0.25pt 0.25pt; vertical-align: bottom; width: 2%">&nbsp;</TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; padding: 0.75pt 2.25pt 0.25pt 0.25pt; width: 84%">&nbsp;</TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">1.
    </FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Name of Reporting Persons</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Koh, Bong</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">2.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check the Appropriate Box if a Member of a Group (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(a) <FONT STYLE="font-family: Wingdings">x</FONT><SUP>1</SUP>
    (b) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">3.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">SEC USE ONLY</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">4.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Citizenship or Place of Organization</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">United States</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD COLSPAN="3" ROWSPAN="4" STYLE="border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.25pt 2.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Number of</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Shares</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Beneficially</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Owned by</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Each</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Reporting</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">With:</P></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">5.
    </FONT></TD>
    <TD STYLE="border-bottom: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">6.</FONT></TD>
    <TD STYLE="border-bottom: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Voting Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: left">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.25pt 2.25pt 0.75pt"><FONT STYLE="font-size: 10pt">7.</FONT></TD>
    <TD STYLE="border-bottom: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Sole Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">0</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-right: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 2.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">8.</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="border-right: black 1.5pt solid; padding: 0.25pt 2.25pt 0.25pt 0.25pt; vertical-align: top"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Shared Dispositive Power</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-top: black 1.5pt solid; border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; vertical-align: top; padding: 0.75pt 0.25pt 0.75pt 9.75pt"><FONT STYLE="font-size: 10pt">9.</FONT></TD>
    <TD STYLE="border-top: black 1.5pt solid; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; vertical-align: bottom; padding: 0.75pt 2.25pt 0.75pt 0.25pt">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-top: black 1.5pt solid; vertical-align: top; border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.75pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Aggregate Amount Beneficially Owned by Each Reporting Person</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9,403,479<SUP>2</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">10.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Check if the Aggregate Amount in Row (9) Excludes Certain Shares
    (See Instructions) <FONT STYLE="font-family: Wingdings">&uml;</FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">11.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Percent of Class Represented by Amount in Row (9)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">9.99%<SUP>3</SUP></P></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="border-bottom: black 1.5pt solid; border-left: black 1.5pt solid; padding: 0.25pt 0.25pt 0.75pt 9.75pt; vertical-align: top"><FONT STYLE="font-size: 10pt">12.</FONT></TD>
    <TD STYLE="border-right: black 1.5pt solid; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt; vertical-align: bottom">&nbsp;</TD>
    <TD COLSPAN="4" STYLE="border-right: black 1.5pt solid; vertical-align: top; border-bottom: black 1.5pt solid; padding: 0.25pt 2.25pt 0.75pt 0.25pt"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Type of Reporting Person (See Instructions)</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">IN</P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 22.5pt; text-indent: -0.25in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">1</TD><TD>Venrock Healthcare Capital Partners II, L.P., VHCP Co-Investment Holdings II, LLC, Venrock Healthcare
                              Capital Partners III, L.P., VHCP Co-Investment Holdings III, LLC, Venrock Healthcare Capital Partners EG,
                              L.P., VHCP Management II, LLC, VHCP Management III, LLC, VHCP Management EG, LLC, Nimish Shah and Bong
                              Koh are members of a group for the purposes of this Schedule 13G/A.</TD></TR>
<TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.25in; text-align: left">2</TD><TD STYLE="text-align: left">Consists of (i) 951,439 shares and 10,586 shares issuable
                                            upon the exercise of immediately exercisable pre-funded warrants (&#8220;Warrants&#8221;)
                                            held by Venrock Healthcare Capital Partners II, L.P., (ii) 385,717 shares and 4,292 shares
                                            issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings II, LLC, (iii)
                                            2,093,431 shares and 23,293 shares issuable upon the exercise of Warrants held by Venrock
                                            Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330 shares issuable upon
                                            the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC and (v) 5,659,991 shares
                                            and 62,977 shares issuable upon the exercise of Warrants held by Venrock Healthcare Capital
                                            Partners EG, L.P. The share numbers in the preceding sentence represent the maximum number
                                            of ordinary shares issuable upon exercise of the Warrants held by the Reporting Persons as
                                            a result of the beneficial ownership provision described in the following sentence. Under
                                            the terms of the Warrants, the Issuer may not effect the exercise of any such Warrant, and
                                            a holder will not be entitled to exercise any portion of such Warrant, if, upon giving effect
                                            to such exercise, the aggregate number of ordinary shares beneficially owned by the holder
                                            (together with its affiliates and other attribution parties) would exceed 9.99% of the number
                                            of ordinary shares outstanding immediately after giving effect to the exercise.</TD>
</TR>
<TR STYLE="vertical-align: top">
<TD STYLE="width: 18pt">3</TD><TD>Based on (i) 94,025,441 Ordinary Shares outstanding as of November 3, 2022 according to information
                              obtained from the Issuer on November 3, 2022 plus (ii) 103,479 shares issuable upon the exercise of the
                              Warrants described in Footnote 2 above.</TD></TR></TABLE>

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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 12 of 17</FONT></TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Introductory Note: This Schedule 13G is filed on behalf of Venrock
Healthcare Capital Partners II, L.P., a limited partnership organized under the laws of the State of Delaware (&#8220;VHCP II LP&#8221;),
VHCP Co-Investment Holdings II, LLC, a limited liability company organized under the laws of the State of Delaware (&#8220;VHCP Co-Investment
II&#8221;), Venrock Healthcare Capital Partners III, L.P., a limited partnership organized under the laws of the State of Delaware (&#8220;VHCP
III LP&#8221;), VHCP Co-Investment Holdings III, LLC, a limited liability company organized under the laws of the State of Delaware (&#8220;VHCP
Co-Investment III&#8221;), Venrock Healthcare Capital Partners EG, L.P., a limited partnership organized under the laws of the State
of Delaware (&#8220;VHCP EG&#8221;), VHCP Management II, LLC, a limited liability company organized under the laws of the State of Delaware
(&#8220;VHCP Management II&#8221;), VHCP Management III, LLC, a limited liability company organized under the laws of the State of Delaware
(&#8220;VHCP Management III&#8221;), VHCP Management EG, LLC, a limited liability company organized under the laws of the State of Delaware
(&#8220;VHCP Management EG&#8221; and collectively with VHCP II LP, VHCP Co-Investment II, VHCP III LP, VHCP Co-Investment III, VHCP
EG, VHCP Management II and VHCP Management III, the &#8220;Venrock Entities&#8221;), Nimish Shah (&#8220;Shah&#8221;) and Bong Koh (&#8220;Koh&#8221;)
in respect of Ordinary Shares of DBV Technologies S.A.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 1.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Name of Issuer</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">DBV Technologies S.A.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Address of Issuer&#8217;s Principal Executive
    Offices</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">177-181 avenue Pierre Brossolette</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">92120 Montrouge France&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 2.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Name of Person Filing</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Venrock Healthcare Capital Partners II, L.P.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Co-Investment Holdings II, LLC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Venrock Healthcare Capital Partners III, L.P.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Co-Investment Holdings III, LLC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Venrock Healthcare Capital Partners EG, L.P.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Management II, LLC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Management III, LLC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">VHCP Management EG, LLC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Nimish Shah</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Bong Koh</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Address of Principal Business Office or,
    if none, Residence</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR>
    <TD STYLE="padding: 0.25pt; width: 12%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 36%"><FONT STYLE="font-size: 10pt">New York Office:</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 52%"><FONT STYLE="font-size: 10pt">Palo Alto Office:</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">7 Bryant Park</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">3340 Hillview Avenue</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">23rd Floor</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Palo Alto, CA 94304</FONT></TD></TR>
  <TR>
    <TD STYLE="padding: 0.25pt">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">New York, NY 10018</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-size: 10pt">(c)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Citizenship</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">All of the Venrock Entities were organized in Delaware. The individuals
are both United States citizens.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 13 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-size: 10pt">(d)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">Title of Class of Securities</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Ordinary shares, &#8364;0.10 nominal value per share (the &#8220;Ordinary
Shares&#8221;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 2%">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 3%"><FONT STYLE="font-size: 10pt">(e)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 95%"><FONT STYLE="font-size: 10pt">CUSIP Number</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">23306J101</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="padding: 0.25pt; width: 6%; text-align: left"><FONT STYLE="font-size: 10pt"><B>Item 3. </B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%; text-align: left"><FONT STYLE="font-size: 10pt"><B>If this statement is filed pursuant to
    &sect;&sect;240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not applicable</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 6%"><FONT STYLE="font-size: 10pt"><B>Item 4.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%"><FONT STYLE="font-size: 10pt"><B>Ownership</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 0.25in">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 0.25in"><FONT STYLE="font-size: 10pt">(a)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Amount Beneficially Owned as of December
    31, 2022:</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 80%; font: 10pt Times New Roman, Times, Serif; margin-left: 0.5in">
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom; width: 82%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners II, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 15%; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Co-Investment Holdings II, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners III, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Co-Investment Holdings III, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners EG, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management II, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management III, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management EG, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Nimish Shah</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Bong Koh</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 0.25in">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 0.25in"><FONT STYLE="font-size: 10pt">(b)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Percent of Class as of December 31, 2022:</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 80%; margin-left: 0.5in">
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="width: 82%; font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners II, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 15%; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Co-Investment Holdings II, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners III, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Co-Investment Holdings III, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners EG, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management II, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management III, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management EG, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Nimish Shah</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">Bong Koh</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">9.99</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">%</TD></TR>
  </TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 0.25in">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 0.25in"><FONT STYLE="font-size: 10pt">(c)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Number of shares as to which the person has, as of
    December 31, 2022:</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 0.25in">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 0.25in"><FONT STYLE="font-size: 10pt">(i)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Sole power to vote or to direct the vote</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 80%; margin-left: 0.5in">
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="width: 82%; font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners II, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 15%; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Co-Investment Holdings II, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners III, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Co-Investment Holdings III, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners EG, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management II, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management III, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management EG, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Nimish Shah</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">Bong Koh</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 14 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 0.25in">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 0.25in"><FONT STYLE="font-size: 10pt">(ii)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Shared power to vote or to direct the vote</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 80%; margin-left: 0.5in">
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom; width: 82%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners II, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 15%; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Co-Investment Holdings II, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners III, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Co-Investment Holdings III, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners EG, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management II, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management III, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management EG, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Nimish Shah</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Bong Koh</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 0.25in">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 0.25in"><FONT STYLE="font-size: 10pt">(iii)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Sole power to dispose or to direct the disposition
    of</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 80%; margin-left: 0.5in">
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="width: 82%; font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners II, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 15%; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; width: 1%; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Co-Investment Holdings II, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners III, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Co-Investment Holdings III, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Venrock Healthcare Capital Partners EG, L.P.</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management II, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management III, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">VHCP Management EG, LLC</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: rgb(204,238,255)">
    <TD STYLE="font-size: 10pt; text-align: left">Nimish Shah</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="font-size: 10pt; text-align: left">Bong Koh</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif">&nbsp;</TD>
    <TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: right">0</TD><TD STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-left: 0.5in; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: white">
    <TD STYLE="padding: 0.25pt; width: 0.25in">&nbsp;</TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top; width: 0.25in"><FONT STYLE="font-size: 10pt">(iv)</FONT></TD>
    <TD STYLE="padding: 0.25pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Shared power to dispose or to direct the disposition
    of</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; border-collapse: collapse; width: 80%; margin-left: 0.5in">
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom; width: 82%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners II, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; width: 15%; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top; width: 1%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Co-Investment Holdings II, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners III, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Co-Investment Holdings III, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Venrock Healthcare Capital Partners EG, L.P.</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management II, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management III, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">VHCP Management EG, LLC</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: #CCEEFF">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Nimish Shah</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  <TR STYLE="background-color: white">
    <TD STYLE="vertical-align: bottom"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Bong Koh</FONT></TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom">&nbsp;</TD>
    <TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">9,403,479 </FONT></TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(1)</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>



<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top; text-align: left">
<TD STYLE="width: 0.5in"></TD><TD STYLE="width: 0.25in; text-align: left">(1)</TD><TD STYLE="text-align: left">Consists of (i) 951,439
                                            shares and 10,586 shares issuable upon the exercise of immediately exercisable pre-funded
                                            warrants (&#8220;Warrants&#8221;) held by Venrock Healthcare Capital Partners II, L.P., (ii)
                                            385,717 shares and 4,292 shares issuable upon the exercise of Warrants held by VHCP Co-Investment
                                            Holdings II, LLC, (iii) 2,093,431 shares and 23,293 shares issuable upon the exercise of
                                            Warrants held by Venrock Healthcare Capital Partners III, L.P., (iv) 209,422 shares and 2,330
                                            shares issuable upon the exercise of Warrants held by VHCP Co-Investment Holdings III, LLC
                                            and (v) 5,659,991 shares and 62,977 shares issuable upon the exercise of Warrants held by
                                            Venrock Healthcare Capital Partners EG, L.P. The share numbers in the preceding sentence
                                            represent the maximum number of ordinary shares issuable upon exercise of the Warrants held
                                            by the Reporting Persons as a result of the beneficial ownership provision described in the
                                            following sentence. Under the terms of the Warrants, the Issuer may not effect the exercise
                                            of any such Warrant, and a holder will not be entitled to exercise any portion of such Warrant,
                                            if, upon giving effect to such exercise, the aggregate number of ordinary shares beneficially
                                            owned by the holder (together with its affiliates and other attribution parties) would exceed
                                            9.99% of the number of ordinary shares outstanding immediately after giving effect to the
                                            exercise. VHCP Management II, LLC is the general partner of Venrock Healthcare Capital Partners
                                            II, L.P. and the manager of VHCP Co-Investment Holdings II, LLC. VHCP Management III, LLC
                                            is the general partner of Venrock Healthcare Capital Partners III, L.P. and the manager of
                                            VHCP Co-Investment Holdings III, LLC. VHCP Management EG, LLC is the general partner of Venrock
                                            Healthcare Capital Partners EG, L.P. Messrs. Shah and Koh are the voting members of VHCP
                                            Management II, LLC, VHCP Management III, LLC and VHCP Management EG, LLC.</TD>
</TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-indent: 0in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-indent: 0in"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-indent: 0in">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-indent: 0in"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 15 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 0.75in; text-indent: 0in">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 6%"><FONT STYLE="font-size: 10pt"><B>Item 5.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%"><FONT STYLE="font-size: 10pt"><B>Ownership of Five Percent or Less of a Class</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; text-align: left; margin: 0pt 0">If this statement is being filed to report the fact
that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities,
check the following <FONT STYLE="font-family: Wingdings">&uml;</FONT>.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 6%"><FONT STYLE="font-size: 10pt"><B>Item 6.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%"><FONT STYLE="font-size: 10pt"><B>Ownership of More than Five Percent on Behalf of Another
    Person</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not Applicable</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 6%"><FONT STYLE="font-size: 10pt"><B>Item 7.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%"><FONT STYLE="font-size: 10pt"><B>Identification and Classification of the Subsidiary Which
    Acquired the Security Being Reported on By the Parent Holding Company or Control Person.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not Applicable</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 6%"><FONT STYLE="font-size: 10pt"><B>Item 8.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%"><FONT STYLE="font-size: 10pt"><B>Identification and Classification of Members of the Group</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not Applicable</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 6%"><FONT STYLE="font-size: 10pt"><B>Item 9.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%"><FONT STYLE="font-size: 10pt"><B>Notice of Dissolution of a Group</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not Applicable</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top; background-color: white">
    <TD STYLE="padding: 0.25pt; width: 6%"><FONT STYLE="font-size: 10pt"><B>Item 10.</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 94%"><FONT STYLE="font-size: 10pt"><B>Certification</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">By signing below I certify that, to the best of my knowledge and belief,
the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing
the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction
having that purpose or effect, other than activities solely in connection with a nomination under &sect; 240.14a-11.&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>




<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 50%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 50%; text-align: right"><FONT STYLE="font-size: 10pt">Page 16 of 17</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><U>SIGNATURE</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">After reasonable inquiry and to the best of my knowledge and belief,
I certify that the information set forth in this statement is true, complete and correct.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Dated: February 14, 2023</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>Venrock Healthcare Capital Partners II, L.P.</B></FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>Venrock Healthcare Capital Partners III, L.P.</B></FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">VHCP Management II, LLC</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">VHCP Management III, LLC</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">General Partner</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">General Partner</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt; width: 5%"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 5%"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 39%"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 2%"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 5%"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 5%"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt; width: 39%"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>VHCP Co-Investment Holdings II, LLC</B></FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>VHCP Co-Investment Holdings III, LLC</B></FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">VHCP Management II, LLC</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">VHCP Management III, LLC</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Manager</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Manager</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD></TR>
  <TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>Venrock Healthcare Capital Partners EG, L.P.</B></FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>VHCP Management EG, LLC</B></FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">VHCP Management EG, LLC</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt; vertical-align: top">By:</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">General Partner</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt; vertical-align: top">By:</TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt; vertical-align: top">&nbsp;</TD>
    <TD STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt; vertical-align: top">&nbsp;</TD>
    <TD STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>

<TR STYLE="font-size: 10pt; vertical-align: top">
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>VHCP Management II, LLC</B></FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>VHCP Management III, LLC</B></FONT></TD></TR>
<TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">David L. Stepp</FONT></TD></TR>
<TR STYLE="font-size: 10pt; vertical-align: top">
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Its:</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">Authorized Signatory</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt; vertical-align: top"></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt"><B>Nimish Shah</B></FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt"><B>Bong Koh</B></FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD COLSPAN="3" STYLE="font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD COLSPAN="3" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt; vertical-align: top">By:</TD>
    <TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; font-size: 10pt; vertical-align: top"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD>
    <TD STYLE="padding-bottom: 1pt; font-size: 10pt"><FONT STYLE="font-size: 10pt">&nbsp;</FONT></TD>
    <TD STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">By: </FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; font-size: 10pt"><FONT STYLE="font-size: 10pt">/s/ David L. Stepp</FONT></TD></TR>
  <TR STYLE="font-size: 10pt">
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">David L. Stepp, as attorney-in-fact</FONT></TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD STYLE="font-size: 10pt">&nbsp;</TD>
    <TD COLSPAN="2" STYLE="font-size: 10pt"><FONT STYLE="font-size: 10pt">David L. Stepp, as attorney-in-fact</FONT></TD></TR>
  </TABLE>
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  <TR STYLE="background-color: #FEFEFE">
    <TD STYLE="padding: 0.25pt; width: 49%"><FONT STYLE="font-size: 10pt"><B>CUSIP No. 23306J101</B></FONT></TD>
    <TD STYLE="padding: 0.25pt; width: 51%; text-align: right"><FONT STYLE="font-size: 10pt">Page 17 of 17</FONT></TD></TR>
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>EXHIBITS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in">A:</TD><TD>Joint Filing Agreement (incorporated by reference to Exhibit B to Schedule
                                            13G filed on June 23, 2022)</TD></TR></TABLE>

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<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in">B:</TD><TD>Power of Attorney for Nimish Shah (incorporated by reference to Exhibit
                                            B to Schedule 13G filed on June 23, 2022)</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in">C:</TD><TD>Power of Attorney for Bong Koh (incorporated by reference to Exhibit B
                                            to Schedule 13G filed on June 23, 2022)</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P>

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