<SEC-DOCUMENT>0000908834-24-000084-index.html : 20240214
<SEC-HEADER>0000908834-24-000084.hdr.sgml : 20240214
<ACCEPTANCE-DATETIME>20240214095429
ACCESSION NUMBER:		0000908834-24-000084
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20240214
DATE AS OF CHANGE:		20240214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Silence Therapeutics plc
		CENTRAL INDEX KEY:			0001479615
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			X0

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-92205
		FILM NUMBER:		24633352

	BUSINESS ADDRESS:	
		STREET 1:		72 HAMMERSMITH ROAD
		CITY:			LONDON
		STATE:			X0
		ZIP:			W14 8TH
		BUSINESS PHONE:		44-0-20-3457 6900

	MAIL ADDRESS:	
		STREET 1:		72 HAMMERSMITH ROAD
		CITY:			LONDON
		STATE:			X0
		ZIP:			W14 8TH

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Lombard Odier Asset Management (USA) Corp
		CENTRAL INDEX KEY:			0001491719
		ORGANIZATION NAME:           	
		IRS NUMBER:				061603711
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		452 FIFTH AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
		BUSINESS PHONE:		212-295-6200

	MAIL ADDRESS:	
		STREET 1:		452 FIFTH AVENUE, 25TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>sln_13ga.htm
<TEXT>
Document 1 - file: sln_13ga.htm

</DOCUMENT>
</SEC-DOCUMENT>