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Summary of Significant Accounting Policies - Additional Information (Details) |  | 12 Months Ended
--- | --- | ---
Feb. 05, 2024 USD ($) OrdinaryShare $ / shares shares | Dec. 31, 2024 USD ($) Segment | Dec. 31, 2023 USD ($) shares | Dec. 31, 2022 USD ($)
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Net loss |  | $ (45,309,000) | $ (54,228,000) | $ (50,334,000)
Accumulated losses |  | 474,044,000 | 431,894,000 |
Cash outflows from operating activities |  | (67,640,000) | (49,462,000) | (57,044,000)
Cash and cash equivalents and short-term investments |  | $ 147,300,000 |  |
Number of reportable segments | Segment |  | 1 |  |
Goodwill impairment loss |  | $ 0 | 0 |
Change in accounting principle, accounting standards update, adopted [true false] |  | true |  |
Accounting standards update [extensible enumeration] |  | us-gaap:AccountingStandardsUpdate202307Member |  |
American Depositary Shares |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Gross proceeds from private placement | $ 120,000,000 |  |  |
Open Market Sale Agreement | American Depositary Shares | Jefferies LLC |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Gross proceeds from sale of stock |  | $ 27,700,000 |  |
Placement agent fees and other expenses |  | 900,000 | $ 1,000,000 |
Sale of stock, number of shares issued | shares |  |  | 3,400,000 |
Gross proceeds from private placement |  | 27,700,000 |  |
Private Placement | American Depositary Shares |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Placement agent fees and other expenses | $ 7,700,000 |  |  |
Sale of stock, number of shares issued | shares | 5,714,286 |  |  |
Number of ordinary shares in American Depositary Share | OrdinaryShare | 3 |  |  |
Sale of stock, price per share | $ / shares | $ 21 |  |  |
Gross proceeds from private placement | $ 120,000,000 |  |  |
Collaboration Agreement with AstraZeneca |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Milestone payments received |  | 10,000,000 | $ 10,000,000 |
Collaboration Agreement with Hansoh |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Milestone payments received |  | $ 2,000,000 | $ 4,000,000 | $ 1,500,000
Minimum | Licenses and Software |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives of intangible assets |  | 3 years |  |
Minimum | Furniture and Equipment |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful life of property, plant and equipment |  | 3 years |  |
Maximum |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Invoice raise duration after quarter end |  | 75 days |  |
Maximum | Licenses and Software |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful lives of intangible assets |  | 10 years |  |
Maximum | Furniture and Equipment |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Estimated useful life of property, plant and equipment |  | 10 years |  |

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