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Shareholders' Equity (Tables) | 12 Months Ended
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Dec. 31, 2024
Stockholders' Equity Note [Abstract] |
Schedule of Shares Outstanding |
|  | Year ended December 31, |
|  | 2024 |  |  | 2023 |  |  | 2022 |
Authorized, allotted, called up and fully paid ordinary shares, par value £0.05 |  |  | 10,288 |  |  |  | 8,847 |  |  |  | 8,151 |
|  | Number |  |  | Number |  |  | Number |
Number of shares in issue |  |  | 141,674,074 |  |  |  | 118,846,966 |  |  |  | 107,808,472 |
Number of ADS in issue |  |  | 47,224,691 |  |  |  | 39,615,655 |  |  |  | 35,936,157 |
Details of Shares Issued | Details of the shares issued during the current and previous year are as follows:
Number of shares in issue at December 31, 2023 |  |  | 118,846,966 |
Number of ADS in issue at December 31, 2023 |  |  | 39,615,655 |
Shares issued during the year |  |  | 21,418,665 |
Options exercised at $0.20/ADS or $0.07/ordinary share |  |  | 252,540 |
Options exercised at $2.40/ADS or $0.80/ordinary share |  |  | 268,791 |
Options exercised at $4.23/ADS or $1.41/ordinary share |  |  | 12,000 |
Options exercised at $4.24/ADS or $1.41/ordinary share |  |  | 9,999 |
Options exercised at $5.81/ADS or $1.94/ordinary share |  |  | 375 |
Options exercised at $7.32/ADS or $2.44/ordinary share |  |  | 30,000 |
Options exercised at $7.60/ADS or $2.53/ordinary share |  |  | 584,316 |
Options exercised at $8.20/ADS or $2.73/ordinary share |  |  | 49,998 |
Options exercised at $9.98/ADS or $3.33/ordinary share |  |  | 222 |
Options exercised at $10.68/ADS or $3.56/ordinary share |  |  | 10,500 |
Options exercised at $12.81/ADS or $4.27/ordinary share |  |  | 1,500 |
Options exercised at $12.94/ADS or $4.31/ordinary share |  |  | 2,841 |
Options exercised at $13.80/ADS or $4.60/ordinary share |  |  | 3,708 |
Options exercised at $15.38/ADS or $5.13/ordinary share |  |  | 126,144 |
Options exercised at $16.64/ADS or $5.55/ordinary share |  |  | 1,248 |
Options exercised at $19.50/ADS or $6.50/ordinary share |  |  | 780 |
Options exercised at $20.41/ADS or $6.80/ordinary share |  |  | 10,500 |
Options exercised at $22.01/ADS or $7.34/ordinary share |  |  | 37,545 |
Options exercised at $23.60/ADS or $7.87/ordinary share |  |  | 5,436 |
Number of shares in issue at December 31, 2024 |  |  | 141,674,074 |
Number of equivalent ADS in issue at December 31, 2024 |  |  | 47,224,691 |
Schedule of Options Outstanding | Details of the options outstanding are as follows:
Year of issue |  | Weighted average Exercise price (£) |  |  | WeightedaverageExerciseprice($) |  |  | At January 1, 2024 |  |  | Options granted |  |  | Options forfeited |  |  | Options expired |  |  | Options exercised |  |  | At December 31, 2024 |  |  | Weighted average years to expiry date |
2014 |  |  | 3.31 |  |  |  | 4.23 |  |  |  | 4,000 |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (4,000 | ) |  |  | - |  |  |  | - |
2015 |  |  | 3.31 |  |  |  | 4.23 |  |  |  | 3,333 |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | 3,333 |  |  |  | 0.51 |
2016 |  |  | 4.02 |  |  |  | 5.14 |  |  |  | 9,857 |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (3,333 | ) |  |  | 6,524 |  |  |  | 1.19 |
2017 |  |  | 6.30 |  |  |  | 8.05 |  |  |  | 39,999 |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (16,666 | ) |  |  | 23,333 |  |  |  | 2.92 |
2018 |  |  | 0.16 |  |  |  | 0.20 |  |  |  | 36,596 |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (6,003 | ) |  |  | 30,593 |  |  |  | 3.26 |
2019 |  |  | 4.19 |  |  |  | 5.36 |  |  |  | 577,698 |  |  |  | - |  |  |  | - |  |  |  | - |  |  |  | (347,701 | ) |  |  | 229,997 |  |  |  | 4.77 |
2020 |  |  | 6.44 |  |  |  | 8.23 |  |  |  | 261,207 |  |  |  | - |  |  |  | (532 | ) |  |  | - |  |  |  | (26,497 | ) |  |  | 234,178 |  |  |  | 5.42 |
2021 |  |  | 17.50 |  |  |  | 22.37 |  |  |  | 662,344 |  |  |  | - |  |  |  | (7,691 | ) |  |  | (62,502 | ) |  |  | (16,015 | ) |  |  | 576,136 |  |  |  | 6.25 |
2022 |  |  | 14.46 |  |  |  | 18.49 |  |  |  | 1,419,863 |  |  |  | - |  |  |  | (27,309 | ) |  |  | (75,037 | ) |  |  | (7,019 | ) |  |  | 1,310,498 |  |  |  | 7.33 |
2023 |  |  | 10.86 |  |  |  | 13.88 |  |  |  | 2,269,589 |  |  |  | - |  |  |  | (63,858 | ) |  |  | (15,127 | ) |  |  | (42,247 | ) |  |  | 2,148,357 |  |  |  | 8.20 |
2024 |  |  | 14.12 |  |  |  | 18.05 |  |  |  | - |  |  |  | 1,267,514 |  |  |  | (12,000 | ) |  |  | - |  |  |  | - |  |  |  | 1,255,514 |  |  |  | 9.06 |
Total (ADSs) |  |  |  |  |  |  |  |  | 5,284,486 |  |  |  | 1,267,514 |  |  |  | (111,390 | ) |  |  | (152,666 | ) |  |  | (469,481 | ) |  |  | 5,818,463 |  |  |  |
Total (Ordinary Shares) |  |  |  |  |  |  |  |  | 15,853,459 |  |  |  | 3,802,542 |  |  |  | (334,170 | ) |  |  | (457,998 | ) |  |  | (1,408,443 | ) |  |  | 17,455,390 |  |  |  |

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