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Shareholders' Equity (Tables)
 12 Months Ended
Dec. 31, 2024
Stockholders' Equity Note [Abstract]  
Schedule of Shares Outstanding

 

Year ended December 31,

 

 

2024

 

 

2023

 

 

2022

 

 

 

 

 

 

 

 

 

 

 

Authorized, allotted, called up and fully paid ordinary shares,
   par value £0.05

 

 

10,288

 

 

 

8,847

 

 

 

8,151

 

 

 

 

 

 

 

 

 

 

 

 

Number

 

 

Number

 

 

Number

 

Number of shares in issue

 

 

141,674,074

 

 

 

118,846,966

 

 

 

107,808,472

 

Number of ADS in issue

 

 

47,224,691

 

 

 

39,615,655

 

 

 

35,936,157

 
Details of Shares Issued

Details of the shares issued during the current and previous year are as follows:

 

Number of shares in issue at December 31, 2023

 

 

118,846,966

 

Number of ADS in issue at December 31, 2023

 

 

39,615,655

 

Shares issued during the year

 

 

21,418,665

 

Options exercised at $0.20/ADS or $0.07/ordinary share

 

 

252,540

 

Options exercised at $2.40/ADS or $0.80/ordinary share

 

 

268,791

 

Options exercised at $4.23/ADS or $1.41/ordinary share

 

 

12,000

 

Options exercised at $4.24/ADS or $1.41/ordinary share

 

 

9,999

 

Options exercised at $5.81/ADS or $1.94/ordinary share

 

 

375

 

Options exercised at $7.32/ADS or $2.44/ordinary share

 

 

30,000

 

Options exercised at $7.60/ADS or $2.53/ordinary share

 

 

584,316

 

Options exercised at $8.20/ADS or $2.73/ordinary share

 

 

49,998

 

Options exercised at $9.98/ADS or $3.33/ordinary share

 

 

222

 

Options exercised at $10.68/ADS or $3.56/ordinary share

 

 

10,500

 

Options exercised at $12.81/ADS or $4.27/ordinary share

 

 

1,500

 

Options exercised at $12.94/ADS or $4.31/ordinary share

 

 

2,841

 

Options exercised at $13.80/ADS or $4.60/ordinary share

 

 

3,708

 

Options exercised at $15.38/ADS or $5.13/ordinary share

 

 

126,144

 

Options exercised at $16.64/ADS or $5.55/ordinary share

 

 

1,248

 

Options exercised at $19.50/ADS or $6.50/ordinary share

 

 

780

 

Options exercised at $20.41/ADS or $6.80/ordinary share

 

 

10,500

 

Options exercised at $22.01/ADS or $7.34/ordinary share

 

 

37,545

 

Options exercised at $23.60/ADS or $7.87/ordinary share

 

 

5,436

 

Number of shares in issue at December 31, 2024

 

 

141,674,074

 

Number of equivalent ADS in issue at December 31, 2024

 

 

47,224,691

 
Schedule of Options Outstanding

Details of the options outstanding are as follows:

 

Year of issue

 

Weighted average Exercise price (£)

 

 

WeightedaverageExerciseprice($)

 

 

At
January 1, 2024

 

 

Options granted

 

 

Options forfeited

 

 

Options expired

 

 

Options exercised

 

 

At
December 31, 2024

 

 

Weighted average years to expiry date

 

2014

 

 

3.31

 

 

 

4.23

 

 

 

4,000

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(4,000

)

 

 

-

 

 

 

-

 

2015

 

 

3.31

 

 

 

4.23

 

 

 

3,333

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

3,333

 

 

 

0.51

 

2016

 

 

4.02

 

 

 

5.14

 

 

 

9,857

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(3,333

)

 

 

6,524

 

 

 

1.19

 

2017

 

 

6.30

 

 

 

8.05

 

 

 

39,999

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(16,666

)

 

 

23,333

 

 

 

2.92

 

2018

 

 

0.16

 

 

 

0.20

 

 

 

36,596

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(6,003

)

 

 

30,593

 

 

 

3.26

 

2019

 

 

4.19

 

 

 

5.36

 

 

 

577,698

 

 

 

-

 

 

 

-

 

 

 

-

 

 

 

(347,701

)

 

 

229,997

 

 

 

4.77

 

2020

 

 

6.44

 

 

 

8.23

 

 

 

261,207

 

 

 

-

 

 

 

(532

)

 

 

-

 

 

 

(26,497

)

 

 

234,178

 

 

 

5.42

 

2021

 

 

17.50

 

 

 

22.37

 

 

 

662,344

 

 

 

-

 

 

 

(7,691

)

 

 

(62,502

)

 

 

(16,015

)

 

 

576,136

 

 

 

6.25

 

2022

 

 

14.46

 

 

 

18.49

 

 

 

1,419,863

 

 

 

-

 

 

 

(27,309

)

 

 

(75,037

)

 

 

(7,019

)

 

 

1,310,498

 

 

 

7.33

 

2023

 

 

10.86

 

 

 

13.88

 

 

 

2,269,589

 

 

 

-

 

 

 

(63,858

)

 

 

(15,127

)

 

 

(42,247

)

 

 

2,148,357

 

 

 

8.20

 

2024

 

 

14.12

 

 

 

18.05

 

 

 

-

 

 

 

1,267,514

 

 

 

(12,000

)

 

 

-

 

 

 

-

 

 

 

1,255,514

 

 

 

9.06

 

Total (ADSs)

 

 

 

 

 

 

 

 

5,284,486

 

 

 

1,267,514

 

 

 

(111,390

)

 

 

(152,666

)

 

 

(469,481

)

 

 

5,818,463

 

 

 

 

Total (Ordinary
   Shares)

 

 

 

 

 

 

 

 

15,853,459

 

 

 

3,802,542

 

 

 

(334,170

)

 

 

(457,998

)

 

 

(1,408,443

)

 

 

17,455,390