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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Cash flow from operating activities      
Net loss $ (45,309) $ (54,228) $ (50,334)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:      
Depreciation expense 336 369 379
Amortization expense 257 252 217
Share-based compensation expense 16,307 16,274 12,686
Net foreign exchange impacts (2,581) 3,962 (1,003)
Other income (4,472) (1,803) (280)
Income tax expense 845 956 688
Change in operating assets and liabilities:      
(Increase)/decrease in trade receivables (904) 392 (723)
(Increase)/decrease in other current assets (1,330) 1,955 (5,199)
Increase in R&D benefit receivable (2,337) (3,403) (9,821)
Decrease/(increase) in other long-term assets 0 (3,217)  
Increase/(decrease) in trade and other payables 499 (473) 2,024
Decrease in contract liabilities (28,786) (10,323) (5,443)
Decrease in operating lease liabilities (165) (175) (235)
Net cash (used in) provided by operating activities (67,640) (49,462) (57,044)
Cash flow from investing activities      
Redemption of term deposits 117,412 45,121  
Purchase of term deposits (139,167) (25,771) (19,953)
Purchase of property, plant and equipment (211) (56) (173)
Purchase of intangible assets     (372)
Net cash (used in) provided by investing activities (21,966) 19,294 (20,498)
Cash flow from financing activities      
Proceeds from issue of ordinary shares 142,087 31,937 52,581
Net cash provided by financing activities 142,087 31,937 52,581
Increase/(decrease) in cash and cash equivalents 52,481 1,769 (24,961)
Cash and cash equivalents at start of period 68,789 66,271 99,351
Effect of exchange rate fluctuations on cash and cash equivalents held 60 749 (8,119)
Cash and cash equivalents, end of period 121,330 68,789 $ 66,271
Supplemental disclosures of cash flow information:      
Tax Paid $ (433) $ (801)