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Summary of Significant Accounting Policies - Additional Information (Details)
 3 Months Ended 12 Months Ended
Feb. 05, 2024
USD ($)
OrdinaryShare
$ / shares
shares
Mar. 31, 2025
USD ($)
Mar. 31, 2024
USD ($)
Dec. 31, 2024
USD ($)
Summary Of Significant Accounting Policies [Line Items]        
Net loss   $ 28,530,000 $ 2,312,000  
Accumulated losses   502,536,000   $ 474,044,000
Cash outflows from operating activities   12,309,000 9,143,000  
Cash and cash equivalents and short-term investments   136,500,000    
American Depositary Shares        
Summary Of Significant Accounting Policies [Line Items]        
Gross proceeds from private placement $ 120,000,000      
Open Market Sale Agreement | American Depositary Shares | Jefferies LLC        
Summary Of Significant Accounting Policies [Line Items]        
Gross proceeds from sale of stock       27,700,000
Placement agent fees and other expenses       900,000
Private Placement | American Depositary Shares        
Summary Of Significant Accounting Policies [Line Items]        
Placement agent fees and other expenses $ 7,700,000      
Sale of stock, number of shares issued | shares 5,714,286      
Number of ordinary shares in American Depositary Share | OrdinaryShare 3      
Sale of stock, price per share | $ / shares $ 21      
Gross proceeds from private placement $ 120,000,000      
Collaboration Agreement with AstraZeneca        
Summary Of Significant Accounting Policies [Line Items]        
Milestone payments received   $ 0 $ 10,000,000 10,000,000
Collaboration Agreement with Hansoh        
Summary Of Significant Accounting Policies [Line Items]        
Milestone payments received       $ 2,000,000