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Revenue - Additional Information (Details) - USD ($)	3 Months Ended		12 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024	Dec. 31, 2023	May 31, 2021	Dec. 31, 2020
Disaggregation of Revenue [Line Items]
Revenue	$ 142,000	$ 15,699,000
Upfront cash payment received	53,683,000		$ 52,096,000	$ 81,572,000
Collaboration Agreement with AstraZeneca
Disaggregation of Revenue [Line Items]
Revenue	100,000	14,700,000
Upfront cash payment received					$ 40,000,000	$ 20,000,000
Milestone payments received	0	10,000,000	$ 10,000,000
Research Collaboration Income
Disaggregation of Revenue [Line Items]
Revenue	$ 142,000	$ 15,556,000

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