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Revenue - Schedule of Disaggregation of Revenue From Contracts With Customers (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	$ 142	$ 15,699
Research Collaboration
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	142	15,556
Research Collaboration | Research Collaboration - Mallinckrodt plc
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	0	578
Research Collaboration | Research Collaboration - AstraZeneca
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	142	14,711
Research Collaboration | Research collaboration - Hansoh
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	0	267
Royalties
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	$ 0	$ 143

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