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Revenue - Schedule of Disaggregation of Revenue From Contracts With Customers (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	$ 159	$ 1,498	$ 525	$ 17,953
Research Collaboration
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	159	1,496	525	17,808
Research Collaboration | Research Collaboration - Mallinckrodt plc
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	0	7	0	585
Research Collaboration | Research Collaboration - AstraZeneca
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	159	1,197	525	16,256
Research Collaboration | Research collaboration - Hansoh
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	0	292	0	967
Royalties
Disaggregation of Revenue [Line Items]
Total revenue from contracts with customers	$ 0	$ 2	$ 0	$ 145

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