<SEC-DOCUMENT>0001415889-25-000108-index.html : 20250102
<SEC-HEADER>0001415889-25-000108.hdr.sgml : 20250102
<ACCEPTANCE-DATETIME>20250102163638
ACCESSION NUMBER:		0001415889-25-000108
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250102
FILED AS OF DATE:		20250102
DATE AS OF CHANGE:		20250102

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ede-Golightly James
		CENTRAL INDEX KEY:			0002048873
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39487
		FILM NUMBER:		25502560

	MAIL ADDRESS:	
		STREET 1:		C/O SILENCE THERAPEUTICS PLC
		STREET 2:		72 HAMMERSMITH ROAD
		CITY:			LONDON
		STATE:			X0
		ZIP:			W14 8TH

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Silence Therapeutics plc
		CENTRAL INDEX KEY:			0001479615
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			X0

	BUSINESS ADDRESS:	
		STREET 1:		72 HAMMERSMITH ROAD
		CITY:			LONDON
		STATE:			X0
		ZIP:			W14 8TH
		BUSINESS PHONE:		44-0-20-3457 6900

	MAIL ADDRESS:	
		STREET 1:		72 HAMMERSMITH ROAD
		CITY:			LONDON
		STATE:			X0
		ZIP:			W14 8TH
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>form3-01022025_090135.xml
<TEXT>
Document 1 - file: form3-01022025_090135.html

Document 1 - RAW XML: form3-01022025_090135.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>ex24-01022025_090136.htm
<TEXT>
Document 2 - file: ex24-01022025_090136.htm

</DOCUMENT>
</SEC-DOCUMENT>