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ACCESSION NUMBER:		0001193125-25-247692
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		11
CONFORMED PERIOD OF REPORT:	20251023
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20251023
DATE AS OF CHANGE:		20251023

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Silence Therapeutics plc
		CENTRAL INDEX KEY:			0001479615
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			X0

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39487
		FILM NUMBER:		251411405

	BUSINESS ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		12 HAMMERSMITH GROVE
		STREET 2:		OFFICE 205
		CITY:			LONDON
		PROVINCE COUNTRY:   	X0
		ZIP:			W6 7AP
		BUSINESS PHONE:		44-0-20-3457 6900

	MAIL ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		12 HAMMERSMITH GROVE
		STREET 2:		OFFICE 205
		CITY:			LONDON
		PROVINCE COUNTRY:   	X0
		ZIP:			W6 7AP
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