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          <link:definition>999041 - Disclosure - We determine the allowance for credit losses by identifying troubled accounts and by using historical experience applied to an aging of accounts, as well as expected losses based on the current and anticipated macroeconomic environment. (Details)</link:definition>
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          <link:definition>999042 - Disclosure - Contract balances for the years ended December 31, 2024, 2023, and 2022 are as follows: (Details)</link:definition>
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          <link:definition>999046 - Disclosure - Related party interest expense consists of the following (Details)</link:definition>
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          <link:definition>999047 - Disclosure - Inventories consist of the following (Details)</link:definition>
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          <link:definition>999050 - Disclosure - Quantitative information regarding the Company&#8217;s leases is as follows: (Details)</link:definition>
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          <link:definition>999052 - Disclosure - The future maturities of the Company&#8217;s operating leases as of December 31, 2024 are as follows: (Details)</link:definition>
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          <link:definition>999053 - Disclosure - Lease Commitments (Details Narrative)</link:definition>
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          <link:definition>999054 - Disclosure - Accrued expenses consist of the following: (Details)</link:definition>
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          <link:definition>999055 - Disclosure - A reconciliation of income tax benefit to the amount computed by applying the Federal income tax rate to loss before provision for income taxes as of December 31, 2024 and 2023 is as follows: (Details)</link:definition>
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          <link:definition>999056 - Disclosure - Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of our deferred income  (Details)</link:definition>
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          <link:definition>999059 - Disclosure - We follow ASC Topic 718, Share-Based Payments, in which compensation expense is recognized only for share-based payments expected to vest. (Details)</link:definition>
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          <link:definition>999060 - Disclosure - The following table illustrates the various assumptions used to calculate the Black-Scholes option pricing model for options granted for all years presented: (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
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          <link:definition>999061 - Disclosure - Additional disclosures for options granted for all years presented: (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
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          <link:definition>999062 - Disclosure - The following table summarizes the option activity for our employees and directors during the year ended December 31, 2024: (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
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          <link:definition>999063 - Disclosure - The aggregate intrinsic value in the table above is based on our closing stock price of $2.26 (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
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          <link:definition>999064 - Disclosure - Stock Options and Stock Grants (Details Narrative)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
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        <link:roleType roleURI="http://nanophase.com/role/KProfit-sharingPlanDetailsNarrative" id="KProfit-sharingPlanDetailsNarrative">
          <link:definition>999065 - Disclosure - 401(k) Profit-Sharing Plan (Details Narrative)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
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          <link:definition>999066 - Disclosure - Revenues from these three customers, as a percentage of total Company revenue, was approximately: (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
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          <link:definition>999067 - Disclosure - Accounts receivable balances for these three customers, as a percentage of total Company accounts receivable, was approximately: (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
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          <link:definition>999068 - Disclosure - Significant Customers (Details Narrative)</link:definition>
          <link:usedOn>link:presentationLink</link:usedOn>
          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
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          <link:definition>999069 - Disclosure - The Chief Operating Decision Maker uses gross profit and net income to evaluate Company performance and in what way to allocate resources. Significant segment expenses, which are the same as the entity as a whole, are as follows: (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
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          <link:definition>999070 - Disclosure - The revenues for 2024 and 2023 by category are as follows: (Details)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
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          <link:usedOn>link:calculationLink</link:usedOn>
          <link:usedOn>link:definitionLink</link:usedOn>
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          <link:definition>999072 - Disclosure - Subsequent Event (Details Narrative)</link:definition>
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          <link:usedOn>link:calculationLink</link:usedOn>
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