<SEC-DOCUMENT>0001354457-11-000128.txt : 20110603
<SEC-HEADER>0001354457-11-000128.hdr.sgml : 20110603
<ACCEPTANCE-DATETIME>20110603103559
ACCESSION NUMBER:		0001354457-11-000128
CONFORMED SUBMISSION TYPE:	25-NSE
CONFIRMING COPY:	
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20110603
DATE AS OF CHANGE:		20110603

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AP PHARMA INC /DE/
		CENTRAL INDEX KEY:			0000818033
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				942875566
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		25-NSE
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221

	BUSINESS ADDRESS:	
		STREET 1:		123 SAGINAW DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063
		BUSINESS PHONE:		6503662626

	MAIL ADDRESS:	
		STREET 1:		123 SAGINAW DRIVE
		STREET 2:		123 SAGINAW DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NASDAQ Stock Market LLC
		CENTRAL INDEX KEY:			0001354457
		IRS NUMBER:				521165937
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		25-NSE

	BUSINESS ADDRESS:	
		STREET 1:		9600 BLACKWELL RD
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850
		BUSINESS PHONE:		301-978-4144

	MAIL ADDRESS:	
		STREET 1:		9600 BLACKWELL RD
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850
</SEC-HEADER>
<DOCUMENT>
<TYPE>25-NSE
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<notificationOfRemoval>

    <schemaVersion>X0203</schemaVersion>

    <exchange>
        <cik>0001354457</cik>
        <entityName>NASDAQ Stock Market LLC</entityName>
    </exchange>

    <issuer>
        <cik>0000818033</cik>
        <entityName>AP PHARMA INC /DE/</entityName>
        <fileNumber>001-33221</fileNumber>
        <address>
            <street1>123 Saginaw Drive</street1>
            <street2></street2>
            <city>Redwood City</city>
            <stateOrCountryCode>CA</stateOrCountryCode>
            <stateOrCountry>CALIFORNIA</stateOrCountry>
            <zipCode>94063</zipCode>
        </address>
        <telephoneNumber>650-366-2626</telephoneNumber>
    </issuer>

    <descriptionClassSecurity>Common Stock</descriptionClassSecurity>

    <ruleProvision>17 CFR 240.12d2-2(b)</ruleProvision>

    <signatureData>
        <signatureName>Amy Horton</signatureName>
        <signatureTitle>Associate General Counsel</signatureTitle>
        <signatureDate>2011-06-03</signatureDate>
    </signatureData>
</notificationOfRemoval>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.25
<SEQUENCE>2
<FILENAME>appadelistreason.txt
<TEXT>
Delisting Determination,The Nasdaq Stock Market, LLC,
June 3, 2011, A.P. Pharma, Inc. The Nasdaq Stock
Market, Inc. (the Exchange) has determined to remove
from listing the common stock of A.P. Pharma, Inc.
(the Company), effective at the opening of the trading
session on June 13, 2011. Based on review of information
provided by the Company, Nasdaq Staff determined that the
Company no longer qualified for listing on the Exchange
pursuant to Listing Rule 5550(a)(2). The Company was
notified of the Staffs determination on November 17, 2010.
The Company appealed the determination to a Hearing Panel.
Upon review of the information provided by the Company,
the Panel issed a decision dated February 28, 2011, granting
the Company continued listing pursuant to an exception
through May 16, 2011, by which date the Company was
required to regain compliance with Listing Rule
5550(a)(2). However, the Company notified the Panel
before that date that it would not regain compliance.
On March 30, 2011, the Panel issued a final delisting
determination and notified the Company that trading in
the Companys securities would be suspended on April 1, 2011.
The Company did not request a review of the Panels decision
by the Nasdaq Listing and Hearing Review Council. The
Listing Council did not call the matter for review.
The Panels Determination to delist the Company became
final on May 16, 2011.
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
