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Statements of Operations (USD $)
In Thousands, except Share data, unless otherwise specified
 12 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
REVENUE      
Contract revenue $ 646 $ 1,301 $ 1,261
OPERATING EXPENSES      
Research and development 8,207 7,264 7,796
General and administrative 3,501 3,971 3,707
Total operating expenses 11,708 11,235 11,503
Operating loss (11,062) (9,934) (10,242)
OTHER INCOME (EXPENSES)      
Gain on sale of royalty interest    2,500   
Other income (loss), net    240 (5)
Interest income (expense), net (373) (2) 29
Total other income (expenses) (373) 2,738 24
Loss from continuing operations before income taxes (11,435) (7,196) (10,218)
Income tax benefit       122
Net loss from continuing operations (11,435) (7,196) (10,096)
Gain (loss) from discontinued operations (379) (150) 68
Net loss $ (11,814) $ (7,346) $ (10,028)
Basic and diluted net loss per share:      
Loss from continuing operations $ (0.10) $ (0.18) $ (0.31)
Net loss $ (0.10) $ (0.19) $ (0.31)
Weighted-average common shares used to compute basic and diluted net loss per share 120,263 39,671 32,625