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NOTE 13 SIGNIFICANT AGREEMENTS (Details Narrative) (USD $) | 12 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010 | Jun. 30, 2011 UpfrontLicenseFeeMember | Dec. 31, 2010 Sale of rights to royalties on sales of Retin-A Micro® and Carac® | Dec. 31, 2007 Sale of rights to royalties on sales of Retin-A Micro® and Carac® | Dec. 31, 2006 Sale of rights to royalties on sales of Retin-A Micro® and Carac®
Revenue related to development services |  | $ 600,000 | $ 1,300,000 | $ 100,000 |  |  |
Revenue from sale |  |  |  |  |  |  | 30,000,000
Proceeds |  |  |  |  | $ 2,500,000 | $ 2,500,000 | $ 25,000,000

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- Definition The amount of cash paid for royalties during the current period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -Subparagraph (g) -URI http://asc.fasb.org/extlink&oid=6943989&loc=d3e3536-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 95 -Paragraph 27 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. + Details
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