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NOTE 8 STOCKHOLDERS' EQUITY - Stock-based compensation expense (Details) (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2010
Operating expenses:
Research and development	$ 1,585	$ 819	$ 398
General and administrative	4,147	1,071	1,351
Total stock-based compensation expense	$ 5,732	$ 1,890	$ 1,749
Impact on basic and diluted net loss per common share	$ 0.02	$ 0.02	$ 0.04