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Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
REVENUE      
Contract revenue    $ 646 $ 1,301
OPERATING EXPENSES      
Research and development 15,045 8,207 7,264
General and administrative 8,786 3,501 3,971
Total operating expenses 23,831 11,708 11,235
Operating loss (23,831) (11,062) (9,934)
OTHER INCOME (EXPENSES)      
Gain on sale of royalty interest       2,500
Other income, net       240
Interest expense, net (599) (373) (2)
Total other income (expenses) (599) (373) 2,738
Loss from continuing operations (24,430) (11,435) (7,196)
Gain (loss) from discontinued operations 1,082 (379) (150)
Net loss $ (23,348) $ (11,814) $ (7,346)
Basic and diluted net loss per share:      
Loss from continuing operations $ (0.10) $ (0.10) $ (0.18)
Net loss $ (0.10) $ (0.10) $ (0.19)
Weighted-average common shares used to compute basic and diluted net loss per share 244,458 120,263 39,671