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NOTE 2 SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Accounting Policies [Abstract]        
Accumulated deficit $ (183,587) $ (160,239)    
Proceeds from common stock financing, net of issuance costs 50,491        
Proceeds from unit financing, net of issuance costs    22,772     
Proceeds from convertible note financing, net of issuance costs 3,000 1,312     
Cash and cash equivalents 53,506 17,974 2,109 7,593
Comprehensive loss $ (23,348) $ (11,814) $ (7,346)