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Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
 12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (23,348) $ (11,814) $ (7,346)
Adjustments to reconcile net loss to net cash used in operating activities:      
Loss (gain) from discontinued operations (1,082) 379 150
Depreciation and amortization 197 179 227
Amortization of debt discount 389 103   
Stock-based compensation 5,732 1,890 1,749
Loss on retirement of fixed assets       4
Changes in operating assets and liabilities:      
Accounts receivable    110 61
Prepaid expenses and other current assets (318) 16 267
Loss on retirement of fixed assets    (77) 75
Accounts payable 984 467 (3)
Accrued expenses 437 1,298 (579)
Deferred revenue    (272) (88)
Net cash used in continuing operating activities (17,009) (7,721) (5,483)
Net cash provided by discontinued operations         
Net cash used in operating activities (17,009) (7,721) (5,483)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of property and equipment (972) (513) (78)
Net cash used in investing activities (972) (513) (78)
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from sale of common stock, net of issuance costs 50,491      
Proceeds from sale of units of common stock and warrants, net of issuance costs    22,772   
Proceeds from convertible note financing, net of issuance costs 3,000 1,312   
Proceeds from the exercise of stock options       47
Proceeds from the issuance of shares under the Employee Stock Purchase Plan 22 15 30
Net cash provided by financing activities 53,513 24,099 77
Net increase (decrease) in cash and cash equivalents 35,532 15,865 (5,484)
Cash and cash equivalents, beginning of year 17,974 2,109 7,593
Cash and cash equivalents, end of year 53,506 17,974 2,109
Supplemental Cash Flow Data:      
Cash paid for interest    $ 2 $ 4