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Note 5 - Stock-Based Compensation
 6 Months Ended
Jun. 30, 2013
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]

 (5)  STOCK-BASED COMPENSATION


The following table summarizes the stock-based compensation expense for all awards (in thousands, except per share amounts):


   

Three Months Ended

June 30,

   

Six Months Ended

June 30,

 
   

2013

   

2012

   

2013

   

2012

 
                                 

Operating expenses:

                               

Research and development

  $ 402     $ 360     $ 544     $ 664  

General and administrative

    2,001       655       3,694       1,129  

Total stock-based compensation expense

  $ 2,403     $ 1,015     $ 4,238     $ 1,793  
                                 

Impact on basic and diluted net loss per common share

  $ 0.01     $ 0.01     $ 0.01     $ 0.01  

The following table summarizes stock option activity for the six months ended June 30, 2013:


   

Shares

(in thousands) 

   

Weighted-

Average

Exercise

Price

   

Weighted-

Average

Remaining

Contractual

Term

(Years)

 
                         

Outstanding at January 1, 2013

    86,478     $ 0.42       8.2  

Granted

    69,732     $ 0.40          

Exercised

    (172 )   $ 0.23          

Expired and forfeited

    (21,097 )   $ 0.56          

Outstanding at June 30, 2013

    134,941     $ 0.39       8.9  

Employee Stock Purchase Plan


We adopted an Employee Stock Purchase Plan (Purchase Plan) in 1997. Qualified employees may elect to have a certain percentage of their salary withheld to purchase shares of our common stock under the Purchase Plan. In June 2011, our stockholders authorized an increase in the number of shares reserved for issuance under the Purchase Plan by 500,000, for a total of 1,000,000 shares reserved at June 30, 2013. The purchase price per share is equal to 85% of the fair market value of the stock on specified dates. Sales under the Purchase Plan during the six months ended June 30, 2013 and 2012 consisted of 80,027 and 58,571 shares at an average price of $0.31 and $0.21, respectively. Shares available for future purchase under the Purchase Plan were 365,674 at June 30, 2013.