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Statements of Stockholders' Equity (USD $) In Thousands, except Share data | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Other Comprehensive Income (Loss) [Member] | Common Stock Issued In Private Placement [Member] | Warrant [Member] | Total
--- | --- | --- | --- | --- | --- | ---
BALANCE, at Dec. 31, 2010 | $ 20 | $ 149,721 | $ (148,425) |  |  | $ 1,316
BALANCE, (in Shares) at Dec. 31, 2010 | 2,007,000 |  |  |  |  |
Net loss |  |  | (11,814) |  |  | (11,814)
Common stock and warrants issued in private placement, net of issuance costs | 80 | 22,692 |  |  |  | 22,772
Common stock and warrants issued in private placement, net of issuance costs (in Shares) | 8,000,000 |  |  |  |  |
Conversion benefit included in convertible notes issued |  | 1,573 |  |  |  | 1,573
Fair value of stock-based compensation for restricted stock awards issued/(cancelled) to directors |  | 98 |  |  |  | 98
Fair value of stock-based compensation for restricted stock awards issued/(cancelled) to directors (in Shares) | (9,000) |  |  |  |  |
Common stock issued to employees under ESPP |  | 15 |  |  |  | 15
Common stock issued to employees under ESPP (in Shares) | 4,000 |  |  |  |  |
Stock-based compensation expense related to stock options and ESPP |  | 1,762 |  |  |  | 1,762
Fair value of warrants issued to non-employee |  | 30 |  |  |  | 30
BALANCE, at Dec. 31, 2011 | 100 | 175,891 | (160,239) |  |  | 15,752
BALANCE, (in Shares) at Dec. 31, 2011 | 10,002,000 |  |  |  |  |
Net loss |  |  | (23,348) |  |  | (23,348)
Common stock issued in private placement, net of issuance costs | 51 | 50,440 |  | 50,491 |  |
Common stock issued in private placement, net of issuance costs (in Shares) | 5,100,000 |  |  |  |  |
Conversion benefit included in convertible notes issued |  | 3,169 |  |  |  | 3,169
Common stock issued to employees under ESPP |  | 22 |  |  |  | 22
Common stock issued to employees under ESPP (in Shares) | 4,000 |  |  |  |  |
Warrant exercise | 1 | (1) |  |  |  |
Warrant exercise (in Shares) | 5,000 |  |  |  |  |
Stock-based compensation expense related to stock options and ESPP |  | 5,552 |  |  |  | 5,552
Fair value of warrants issued to non-employee |  | 180 |  |  |  | 180
BALANCE, at Dec. 31, 2012 | 152 | 235,253 | (183,587) |  |  | 51,818
BALANCE, (in Shares) at Dec. 31, 2012 | 15,111,000 |  |  |  |  |
Net loss |  |  | (55,283) |  |  | (55,283)
Common stock issued in private placement, net of issuance costs | 77 | 57,725 |  | 57,802 |  |
Common stock issued in private placement, net of issuance costs (in Shares) | 7,706,000 |  |  |  |  |
Conversion benefit included in convertible notes issued |  | 291 |  |  |  | 291
Common stock issued to employees under ESPP | 1 | 33 |  |  |  | 34
Common stock issued to employees under ESPP (in Shares) | 6,000 |  |  |  |  |
Common stock issued for stock option exercises | 5 | 2,788 |  |  |  | 2,793
Common stock issued for stock option exercises (in Shares) | 537,000 |  |  |  |  | 537,029
Warrant exercise | 2 | 598 |  |  | 600 |
Warrant exercise (in Shares) | 212,000 |  |  |  |  |
Stock-based compensation expense related to stock options and ESPP |  | 10,890 |  |  |  | 10,890
BALANCE, at Dec. 31, 2013 | $ 237 | $ 307,578 | $ (238,870) |  |  | $ 68,945
BALANCE, (in Shares) at Dec. 31, 2013 | 23,572,000 |  |  |  |  |

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