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Note 14 - Quarterly Results of Operations (Unaudited) (Tables) | 12 Months Ended
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Dec. 31, 2013 | Dec. 31, 2012
Quarterly Financial Information Disclosure [Abstract] |  |
Schedule of Quarterly Financial Information [Table Text Block] |
Year Ended December 31, 2013 |  | First Quarter |  |  | Second Quarter |  |  | Third Quarter |  |  | Fourth Quarter |
Total revenue |  | $ | - |  |  | $ | - |  |  | $ | - |  |  | $ | - |
Operating expenses |  |  | 12,752 |  |  |  | 15,209 |  |  |  | 12,664 |  |  |  | 13,832 |
Interest and other expense, net |  |  | (201 | ) |  |  | (204 | ) |  |  | (209 | ) |  |  | (212 | )
Net loss |  |  | (12,953 | ) |  |  | (15,413 | ) |  |  | (12,873 | ) |  |  | (14,044 | )
Basic and diluted net loss per share: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | $ | (0.85 | ) |  | $ | (1.01 | ) |  | $ | (0.84 | ) |  | $ | (0.75 | )
Year Ended December 31, 2012 |  | First Quarter |  |  | Second Quarter |  |  | Third Quarter |  |  | Fourth Quarter |
Total revenue |  | $ | - |  |  | $ | - |  |  | $ | - |  |  | $ | - |
Operating expenses |  |  | 4,769 |  |  |  | 4,380 |  |  |  | 6,054 |  |  |  | 8,628 |
Interest and other expense, net |  |  | (61 | ) |  |  | (146 | ) |  |  | (195 | ) |  |  | (197 | )
Loss from continuing operations |  |  | (4,830 | ) |  |  | (4,526 | ) |  |  | (6,249 | ) |  |  | (8,825 | )
Discontinued operations |  |  | (91 | ) |  |  | (43 | ) |  |  | 128 |  |  |  | 1,088 |
Net loss |  |  | (4,921 | ) |  |  | (4,569 | ) |  |  | (6,121 | ) |  |  | (7,737 | )
Basic and diluted net loss per share: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Loss from continuing operations |  | $ | (0.48 | ) |  | $ | (0.45 | ) |  | $ | (0.46 | ) |  | $ | (0.58 | )
Net loss |  |  | (0.49 | ) |  |  | (0.46 | ) |  |  | (0.45 | ) |  |  | (0.51 | )

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- Definition Tabular disclosure of the quarterly financial data in the annual financial statements. The disclosure includes financial information for each fiscal quarter for the current and previous year, including revenues, gross profit, income (loss) before extraordinary items and cumulative effect of a change in accounting principle and earnings per share data. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=25249566&loc=d3e1280-108306 + Details
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