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Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding (USD $)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Number Outstanding - Options Outstanding (in Shares) 6,355,681 4,323,874 2,505,283 160,833
Weight-average Remaining Contractual Life - Options Outstanding 8 years 51 days      
Weight-average Exercise Price - Options Outstanding $ 8.22 $ 8.46 $ 6.13 $ 29.83
$3.80 to $3.80 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 3.80      
Upper Range of Exercise Price $ 3.80      
Number Outstanding - Options Outstanding (in Shares) 5,000      
Weight-average Remaining Contractual Life - Options Outstanding 7 years 361 days      
Weight-average Exercise Price - Options Outstanding $ 3.80      
Number Exercisable - Options Exercisable (in Shares) 2,708      
Weighted-average Exercise Price - Options Exercisable $ 3.80      
$5.20 to $5.20 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 5.20      
Upper Range of Exercise Price $ 5.20      
Number Outstanding - Options Outstanding (in Shares) 1,072,887      
Weight-average Remaining Contractual Life - Options Outstanding 4 years 7 days      
Weight-average Exercise Price - Options Outstanding $ 5.20      
Number Exercisable - Options Exercisable (in Shares) 997,934      
Weighted-average Exercise Price - Options Exercisable $ 5.20      
$6.40 to $7.00 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 6.40      
Upper Range of Exercise Price $ 7.00      
Number Outstanding - Options Outstanding (in Shares) 386,613      
Weight-average Remaining Contractual Life - Options Outstanding 8 years 219 days      
Weight-average Exercise Price - Options Outstanding $ 6.85      
Number Exercisable - Options Exercisable (in Shares) 80,210      
Weighted-average Exercise Price - Options Exercisable $ 6.66      
$7.20 to $7.20 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 7.20      
Upper Range of Exercise Price $ 7.20      
Number Outstanding - Options Outstanding (in Shares) 3,190,240      
Weight-average Remaining Contractual Life - Options Outstanding 9 years 124 days      
Weight-average Exercise Price - Options Outstanding $ 7.20      
Number Exercisable - Options Exercisable (in Shares) 41,012      
Weighted-average Exercise Price - Options Exercisable $ 7.20      
$7.40 to $10.60 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 7.40      
Upper Range of Exercise Price $ 10.60      
Number Outstanding - Options Outstanding (in Shares) 852,372      
Weight-average Remaining Contractual Life - Options Outstanding 9 years 138 days      
Weight-average Exercise Price - Options Outstanding $ 9.89      
Number Exercisable - Options Exercisable (in Shares) 105,881      
Weighted-average Exercise Price - Options Exercisable $ 10.57      
$11.00 to $15.00 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 11.00      
Upper Range of Exercise Price $ 15.00      
Number Outstanding - Options Outstanding (in Shares) 730,285      
Weight-average Remaining Contractual Life - Options Outstanding 7 years 197 days      
Weight-average Exercise Price - Options Outstanding $ 13.15      
Number Exercisable - Options Exercisable (in Shares) 499,642      
Weighted-average Exercise Price - Options Exercisable $ 12.79      
$15.40 to $130.40 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 15.40      
Upper Range of Exercise Price $ 130.40      
Number Outstanding - Options Outstanding (in Shares) 117,598      
Weight-average Remaining Contractual Life - Options Outstanding 6 years 160 days      
Weight-average Exercise Price - Options Outstanding $ 24.14      
Number Exercisable - Options Exercisable (in Shares) 42,524      
Weighted-average Exercise Price - Options Exercisable $ 39.54      
$139.20 to $139.20 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 139.20      
Upper Range of Exercise Price $ 139.20      
Number Outstanding - Options Outstanding (in Shares) 125      
Weight-average Remaining Contractual Life - Options Outstanding 1 year 29 days      
Weight-average Exercise Price - Options Outstanding $ 139.20      
Number Exercisable - Options Exercisable (in Shares) 125      
Weighted-average Exercise Price - Options Exercisable $ 139.20      
$196.00 to $196.00 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 196.00      
Upper Range of Exercise Price $ 196.00      
Number Outstanding - Options Outstanding (in Shares) 436      
Weight-average Remaining Contractual Life - Options Outstanding 14 days      
Weight-average Exercise Price - Options Outstanding $ 196.00      
Number Exercisable - Options Exercisable (in Shares) 436      
Weighted-average Exercise Price - Options Exercisable $ 196.00      
$235.12 to $235.12 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 235.12      
Upper Range of Exercise Price $ 235.12      
Number Outstanding - Options Outstanding (in Shares) 125      
Weight-average Remaining Contractual Life - Options Outstanding 146 days      
Weight-average Exercise Price - Options Outstanding $ 235.12      
Number Exercisable - Options Exercisable (in Shares) 125      
Weighted-average Exercise Price - Options Exercisable $ 235.12      
$3.80 to $235.12 [Member]
       
Note 8 - Stockholders' Equity (Details) - Stock Options Outstanding [Line Items]        
Lower Range of Exercise Price $ 3.80      
Upper Range of Exercise Price $ 235.12      
Number Outstanding - Options Outstanding (in Shares) 6,355,681      
Weight-average Remaining Contractual Life - Options Outstanding 8 years 51 days      
Weight-average Exercise Price - Options Outstanding $ 8.22      
Number Exercisable - Options Exercisable (in Shares) 1,770,597      
Weighted-average Exercise Price - Options Exercisable $ 8.67