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Note 8 - Stockholders' Equity (Details) - Common Shares Reserved
Dec. 31, 2013
Note 8 - Stockholders' Equity (Details) - Common Shares Reserved [Line Items]  
Common stock reserved for future issuance 22,023,232
Issuance Upon Exercise of Outstanding Stock Options [Member]
  
Note 8 - Stockholders' Equity (Details) - Common Shares Reserved [Line Items]  
Common stock reserved for future issuance 6,355,681
Employee Stock Option [Member]
  
Note 8 - Stockholders' Equity (Details) - Common Shares Reserved [Line Items]  
Common stock reserved for future issuance 1,797,694
Employee Stock Purchase Plan [Member]
  
Note 8 - Stockholders' Equity (Details) - Common Shares Reserved [Line Items]  
Common stock reserved for future issuance 16,651
Issuance of Common Stock Related to Convertible Notes [Member]
  
Note 8 - Stockholders' Equity (Details) - Common Shares Reserved [Line Items]  
Common stock reserved for future issuance 9,884,342 [1]
Issuance Upon Exercise of Warrants [Member]
  
Note 8 - Stockholders' Equity (Details) - Common Shares Reserved [Line Items]  
Common stock reserved for future issuance 3,968,864
[1] Assumes all interest payments are paid-in-kind through the maturity date.