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Statements of Stockholders' Equity (USD $)
In Thousands, except Share data
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Common Stock Issued In Private Placement [Member]
Warrant [Member]
Total
BALANCE, at Dec. 31, 2010 $ 20 $ 149,721 $ (148,425)     $ 1,316
BALANCE, (in Shares) at Dec. 31, 2010 2,007,000          
Net loss     (11,814)     (11,814)
Common stock and warrants issued in private placement, net of issuance costs 80 22,692       22,772
Common stock and warrants issued in private placement, net of issuance costs (in Shares) 8,000,000          
Conversion benefit included in convertible notes issued   1,573       1,573
Fair value of stock-based compensation for restricted stock awards issued/(cancelled) to directors   98       98
Fair value of stock-based compensation for restricted stock awards issued/(cancelled) to directors (in Shares) (9,000)          
Common stock issued to employees under ESPP   15       15
Common stock issued to employees under ESPP (in Shares) 4,000          
Stock-based compensation expense related to stock options and ESPP   1,762       1,762
Fair value of warrants issued to non-employee   30       30
BALANCE, at Dec. 31, 2011 100 175,891 (160,239)     15,752
BALANCE, (in Shares) at Dec. 31, 2011 10,002,000          
Net loss     (23,348)     (23,348)
Common stock issued in private placement, net of issuance costs 51 50,440   50,491    
Common stock issued in private placement, net of issuance costs (in Shares) 5,100,000          
Conversion benefit included in convertible notes issued   3,169       3,169
Common stock issued to employees under ESPP   22       22
Common stock issued to employees under ESPP (in Shares) 4,000          
Warrant exercise 1 (1)        
Warrant exercise (in Shares) 5,000          
Stock-based compensation expense related to stock options and ESPP   5,552       5,552
Fair value of warrants issued to non-employee   180       180
BALANCE, at Dec. 31, 2012 152 235,253 (183,587)     51,818
BALANCE, (in Shares) at Dec. 31, 2012 15,111,000          
Net loss     (55,283)     (55,283)
Common stock issued in private placement, net of issuance costs 77 57,725   57,802    
Common stock issued in private placement, net of issuance costs (in Shares) 7,706,000          
Conversion benefit included in convertible notes issued   291       291
Common stock issued to employees under ESPP 1 33       34
Common stock issued to employees under ESPP (in Shares) 6,000          
Common stock issued for stock option exercises 5 2,788       2,793
Common stock issued for stock option exercises (in Shares) 537,000         537,029
Warrant exercise 2 598     600  
Warrant exercise (in Shares) 212,000          
Stock-based compensation expense related to stock options and ESPP   10,890       10,890
BALANCE, at Dec. 31, 2013 $ 237 $ 307,578 $ (238,870)     $ 68,945
BALANCE, (in Shares) at Dec. 31, 2013 23,572,000