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Note 14 - Quarterly Results of Operations (Unaudited) (Details) - Quarterly Results of 2013 Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
3 Months Ended 12 Months Ended
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2012
Mar. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Quarterly Results of 2013 Operations [Abstract]                      
Total revenue $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0 $ 0     $ 646
Operating expenses 13,832 12,664 15,209 12,752 8,628 6,054 4,380 4,769 54,457 23,831 11,708
Interest and other expense, net (212) (209) (204) (201) (197) (195) (146) (61) (826) (599) (373)
Net loss $ (14,044) $ (12,873) $ (15,413) $ (12,953) $ (7,737) $ (6,121) $ (4,569) $ (4,921) $ (55,283) $ (23,348) $ (11,814)
Net loss (in Dollars per share) $ (0.75) $ (0.84) $ (1.01) $ (0.85) $ (0.51) $ (0.45) $ (0.46) $ (0.49) $ (3.42) $ (1.91) $ (1.96)