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Statements of Cash Flows (USD $)
 12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (55,283,000) $ (23,348,000) $ (11,814,000)
Adjustments to reconcile net loss to net cash used in operating activities:      
(Gain) loss from discontinued operations   (1,082,000) 379,000
Depreciation and amortization 333,000 197,000 179,000
Amortization of debt discount 533,000 389,000 103,000
Stock-based compensation expense 10,890,000 5,732,000 1,890,000
Changes in operating assets and liabilities:      
Accounts receivable     110,000
Prepaid expenses and other current assets (54,000) (318,000) 16,000
Other long-term assets     (77,000)
Accounts payable (426,000) 984,000 467,000
Accrued expenses 3,244,000 437,000 1,298,000
Deferred revenue     (272,000)
Net cash used in operating activities (40,763,000) (17,009,000) (7,721,000)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of property and equipment (1,685,000) (972,000) (513,000)
Net cash used in investing activities (1,685,000) (972,000) (513,000)
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from sale of common stock, net of issuance costs 57,802,000 50,491,000  
Proceeds from sale of units of common stock and warrants, net of issuance costs     22,772,000
Proceeds from convertible note financing, net of issuance costs   3,000,000 1,312,000
Proceeds from warrant exercises 600,000    
Proceeds from the exercise of stock options 2,793,000 0 0
Proceeds from the issuance of shares under the Employee Stock Purchase Plan 34,000 22,000 15,000
Net cash provided by financing activities 61,229,000 53,513,000 24,099,000
Net increase in cash and cash equivalents 18,781,000 35,532,000 15,865,000
Cash and cash equivalents, beginning of year 53,506,000 17,974,000 2,109,000
Cash and cash equivalents, end of year 72,287,000 53,506,000 17,974,000
Supplemental Cash Flow Data:      
Cash paid for interest     $ 2,000