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Note 11 - Summary of Quarterly Financial Data (Unaudited) (Tables)

12 Months Ended

Dec. 31, 2014

Quarterly Financial Information Disclosure [Abstract]

Schedule of Quarterly Financial Information [Table Text Block]

		2014
		First Quarter				Second Quarter				Third Quarter				Fourth Quarter
		(In thousands, except per share amounts)
Operating expenses:
Research and development		$	11,628			$	14,279			$	14,731			$	14,195
General and administrative			5,694				4,512				4,222				5,300
Loss from operations			(17,322	)			(18,791	)			(18,953	)			(19,495	)
Interest income			—				—				—				3
Interest expense			(216	)			(220	)			(224	)			(227	)
Other expense			—				—				(17	)			(905	)
Net loss		$	(17,538	)		$	(19,011	)		$	(19,194	)		$	(20,624	)
Basis and diluted net loss per share		$	(0.74	)		$	(0.78	)		$	(0.66	)		$	(0.71	)

		2013
		First Quarter				Second Quarter				Third Quarter				Fourth Quarter
		(In thousands, except per share amounts)
Operating expenses:
Research and development		$	7,065			$	10,748			$	6,165			$	8,538
General and administrative			5,687				4,461				6,500				5,293
Loss from operations			(12,752	)			(15,209	)			(12,665	)			(13,831	)
Interest income			1				1				—				—
Interest expense			(202	)			(205	)			(209	)			(212	)
Other expense			—				—				—				—
Net loss		$	(12,953	)		$	(15,413	)		$	(12,874	)		$	(14,043	)
Basis and diluted net loss per share		$	(0.85	)		$	(1.01	)		$	(0.84	)		$	(0.75	)

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- Definition

Tabular disclosure of the quarterly financial data in the annual financial statements. The disclosure includes financial information for each fiscal quarter for the current and previous year, including revenues, gross profit, income (loss) before extraordinary items and cumulative effect of a change in accounting principle and earnings per share data.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 270

-SubTopic 10

-Section 50

-Paragraph 1

-Subparagraph (a)-(j)

-URI http://asc.fasb.org/extlink&oid=35737889&loc=d3e1280-108306

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