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Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Operating expenses:
Research and development	$ 54,833us-gaap_ResearchAndDevelopmentExpense	$ 32,516us-gaap_ResearchAndDevelopmentExpense	$ 15,174us-gaap_ResearchAndDevelopmentExpense
General and administrative	19,728us-gaap_GeneralAndAdministrativeExpense	21,941us-gaap_GeneralAndAdministrativeExpense	8,657us-gaap_GeneralAndAdministrativeExpense
Total operating expenses	74,561us-gaap_OperatingExpenses	54,457us-gaap_OperatingExpenses	23,831us-gaap_OperatingExpenses
Loss from operations	(74,561)us-gaap_OperatingIncomeLoss	(54,457)us-gaap_OperatingIncomeLoss	(23,831)us-gaap_OperatingIncomeLoss
Other income (expense):
Interest expense	(887)us-gaap_InterestExpense	(828)us-gaap_InterestExpense	(605)us-gaap_InterestExpense
Other income (expense), net	(919)us-gaap_OtherNonoperatingIncomeExpense	2us-gaap_OtherNonoperatingIncomeExpense	6us-gaap_OtherNonoperatingIncomeExpense
Total other income (expense)	(1,806)us-gaap_NonoperatingIncomeExpense	(826)us-gaap_NonoperatingIncomeExpense	(599)us-gaap_NonoperatingIncomeExpense
Loss from continuing operations	(76,367)us-gaap_IncomeLossFromContinuingOperations	(55,283)us-gaap_IncomeLossFromContinuingOperations	(24,430)us-gaap_IncomeLossFromContinuingOperations
Gain from discontinued operations			1,082us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity
Net loss	$ (76,367)us-gaap_NetIncomeLoss	$ (55,283)us-gaap_NetIncomeLoss	$ (23,348)us-gaap_NetIncomeLoss
Basic and diluted net loss per share:
Loss from continuing operations (in Dollars per share)	$ (2.87)us-gaap_IncomeLossFromContinuingOperationsPerBasicAndDilutedShare	$ (3.42)us-gaap_IncomeLossFromContinuingOperationsPerBasicAndDilutedShare	$ (2.00)us-gaap_IncomeLossFromContinuingOperationsPerBasicAndDilutedShare
Net loss (in Dollars per share)	$ (2.87)us-gaap_EarningsPerShareBasicAndDiluted	$ (3.42)us-gaap_EarningsPerShareBasicAndDiluted	$ (1.91)us-gaap_EarningsPerShareBasicAndDiluted
Shares used in computing basic and diluted net loss per share (in Shares)	26,569us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted	16,163us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted	12,223us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted

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