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Condensed Consolidated Statements of Operations (Unaudited) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2015	Mar. 31, 2014
Operating expenses:
Research and development	$ 14,504us-gaap_ResearchAndDevelopmentExpense	$ 11,628us-gaap_ResearchAndDevelopmentExpense
General and administrative	5,856us-gaap_GeneralAndAdministrativeExpense	5,694us-gaap_GeneralAndAdministrativeExpense
Total operating expenses	20,360us-gaap_OperatingExpenses	17,322us-gaap_OperatingExpenses
Loss from operations	(20,360)us-gaap_OperatingIncomeLoss	(17,322)us-gaap_OperatingIncomeLoss
Interest expense, net	(210)us-gaap_NonoperatingIncomeExpense	(216)us-gaap_NonoperatingIncomeExpense
Net loss	$ (20,570)us-gaap_NetIncomeLoss	$ (17,538)us-gaap_NetIncomeLoss
Basic and diluted net loss per share (in dollars per share)	$ (0.70)us-gaap_EarningsPerShareBasicAndDiluted	$ (0.74)us-gaap_EarningsPerShareBasicAndDiluted
Shares used in computing basic and diluted net loss per share (in shares)	29,392us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted	23,686us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted

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The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line.

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