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Note 5 - Stockholders' Equity (Details Textual) - USD ($)
 1 Months Ended 6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Nov. 30, 2013
Jun. 30, 2011
Jun. 30, 2015
Jun. 30, 2014
Private Placement 2011 [Member] | Common Stock [Member]            
Stock Issued During Period, Shares, New Issues         209,607 108,409
Private Placement 2011 [Member] | Warrant [Member]            
Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Exercised         260,480 144,040
Private Placement 2011 [Member]            
Proceeds from Warrant Exercises         $ 0 $ 0
Class of Warrant or Right, Number of Securities Called by Warrants or Rights       4,000,000    
Class of Warrant or Right, Exercise Price of Warrants or Rights       $ 3.60    
Beneficial Ownership after Conversion       9.99%    
Notice Period Associated with Beneficial Ownership Percentage Limitation Convertible Notes       61 days    
Class of Warrant or Right, Outstanding 3,048,810       3,048,810  
Common Stock [Member] | Jefferies, LLC [Member]            
Stock Issued During Period, Shares, New Issues     7,700,000      
Sale of Stock, Price Per Share     $ 8      
Proceeds from Issuance of Common Stock     $ 57,800,000      
Payments of Stock Issuance Costs     $ 3,900,000      
Common Stock [Member]            
Stock Issued During Period, Shares, New Issues 5,500,000 4,800,000        
Sale of Stock, Price Per Share $ 24.75 $ 11.75     $ 24.75 $ 11.75
Payments of Stock Issuance Costs $ 8,400,000          
Proceeds from Issuance or Sale of Equity 128,200,000          
Common Stock and Prefunded Warrants [Member]            
Payments of Stock Issuance Costs   $ 4,000,000        
Proceeds from Issuance or Sale of Equity   $ 58,900,000        
Pre-funded Warrants[Member]            
Class of Warrant or Right, Number of Securities Called by Warrants or Rights   600,000       600,000
Share Price   $ 11.74       $ 11.74
Class of Warrant or Right, Exercise Price of Warrants or Rights   $ 0.01       $ 0.01
Proceeds from Issuance or Sale of Equity         $ 128,205,000 $ 58,922,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Net         713,381 438,255
Proceeds from Stock Options Exercised         $ 6,306,000 $ 2,308,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period         713,000 504,217
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized $ 28,358,000       $ 28,358,000  
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition         2 years 73 days