<SEC-DOCUMENT>0001299933-15-001471.txt : 20151013
<SEC-HEADER>0001299933-15-001471.hdr.sgml : 20151012
<ACCEPTANCE-DATETIME>20151013145627
ACCESSION NUMBER:		0001299933-15-001471
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20151012
ITEM INFORMATION:		Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20151013
DATE AS OF CHANGE:		20151013

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
		CENTRAL INDEX KEY:			0000818033
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				942875566
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33221
		FILM NUMBER:		151155903

	BUSINESS ADDRESS:	
		STREET 1:		123 SAGINAW DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063
		BUSINESS PHONE:		6503662626

	MAIL ADDRESS:	
		STREET 1:		123 SAGINAW DRIVE
		STREET 2:		123 SAGINAW DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
		DATE OF NAME CHANGE:	20010511

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703
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<TYPE>8-K
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<FILENAME>htm_52523.htm
<DESCRIPTION>LIVE FILING
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<TITLE> Heron Therapeutics, Inc. (Form: 8-K) </TITLE>
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		UNITED STATES<BR>
	SECURITIES AND EXCHANGE COMMISSION
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	WASHINGTON, D.C. 20549
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	FORM 8-K
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	CURRENT REPORT
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	Pursuant to Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934
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	Date of Report (Date of Earliest Event Reported):
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	October 12, 2015
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	Heron Therapeutics, Inc.
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	(Exact name of registrant as specified in its charter)
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	Delaware
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	001-33221
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	94-2875566
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_____________________<BR>
	(State or other jurisdiction
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	of incorporation)
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	Identification No.)
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	123 Saginaw Drive, Redwood City, California
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	94063
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	650-366-2626
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	Not Applicable
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	Former name or former address, if changed since last report
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	&nbsp;
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Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any
of the following provisions:</FONT>
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[&nbsp;&nbsp;]&nbsp;&nbsp;Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))<br>
[&nbsp;&nbsp;]&nbsp;&nbsp;Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))<br>
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	Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
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On October 12, 2015, Heron Therapeutics, Inc. (the "Company") announced the appointment of Neil J. Clendeninn, M.D., Ph.D., as Senior Vice President and Chief Medical Officer ("CMO"), as described in the press release furnished herewith as Exhibit 99.1. Dr. Clendeninn, 66, brings over 30 years of experience in drug development and clinical practice. Since 2001, Dr. Clendeninn has been the president of CANAID, Inc. his own consultancy firm, and prior to joining Heron, he was an advisor to the Company in that capacity. Additionally, Dr. Clendeninn is currently a practicing physician and serves as Program Director for Palliative Medicine Partners: Complex Illness Coordination, a program of Kauai Hospice in Kauai, Hawaii. <br><br>Dr. Clendeninn will receive an annual salary of $400,000 and is eligible for a target bonus of 40% of his salary. In connection with his appointment as CMO, Dr. Clendeninn was granted options to purchase a total of up to 150,000 shares of the Company's common stock.  Such options shall vest and become exercisable with respect to 25,000 shares on the first anniversary of his first day of employment (the "Grant Date"), followed by 75,000 shares vesting ratably each month over the subsequent three years, such that 100,000 options will be fully vested on the four year anniversary of the Grant Date.  The remaining 50,000 shares shall vest and become exercisable in full upon approval of SUSTOL&#174; (granisetron) Injection, extended release by the U.S. Food and Drug Administration. Dr. Clendeninn's options were granted under the Company&#x2019;s Amended and Restated 2007 Equity Incentive Plan, and have a ten year term.<br><br>In accordance with the terms of Dr. Clendeninn's Executive Employment Agreement, dated October 12, 2015 (the "Clendeninn Agreement") if Dr. Clendeninn's employment is terminated by the Company without "Cause" (as defined), or by Dr. Clendeninn for "Good Reason" (as defined), then he shall be entitled to receive: (i) a lump-sum payment equal to the sum of his annual base salary then in effect and his target performance bonus then in effect, less required deductions and withholdings; and (ii) accelerated time-based vesting of shares subject to all stock awards issued by the Company, for the number of shares that would have vested accordingly had he continued employment with the Company for a period of twelve months after termination (which includes partial accelerated vesting of awards subject to time-vesting, but does not include awards that remain subject to performance criteria as of the date of termination). The Company also agreed to reimburse for or continue to pay for health care benefits during the 12 months after the date of termination, or such date when he is no longer eligible for such benefits under applicable law. Per the Clendeninn Agreement, in the event Dr. Clendeninn's employment was terminated by the Company without Cause, or if he resigned for Good Reason within three months before, or within eighteen months following, a Change in Control (as defined) of the Company, then, in lieu of the above benefits, Dr. Clendeninn would have been entitled to receive: (i) a lump sum payment equal to his annual base salary then in effect, less required deductions and withholdings; and (ii) the greater of his target performance bonus then in effect, less required deductions and withholdings, or his performance bonus paid in the year preceding the year in which termination occurs, less required deductions and withholdings. The Company also agreed to reimburse for or continue to pay for health care benefits during the 12 months after the date of termination, or such date when he is no longer eligible for such benefits under applicable law.  <br>
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	Item 9.01 Financial Statements and Exhibits.
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(d) Exhibits. <br> <br>		<br>Exhibit No./ Description<br>	<br>99.1	  Press Release, dated October 12, 2015<br>
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	SIGNATURES
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	Pursuant to the requirements of the Securities Exchange Act of 1934, the
	registrant has duly caused this report to be signed on its behalf by the
	undersigned hereunto duly authorized.
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	Heron Therapeutics, Inc.
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	October 13, 2015
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	/s/ Esme C. Smith
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	Name: Esme C. Smith
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	Title: VP, General Counsel & Secretary
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	Exhibit&nbsp;Index
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	99.1
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Press Release, dated October 12, 2015
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<P align="left" style="font-size: 10pt"><FONT style="font-size: 12pt">EXHIBIT 99.1
</FONT>

<P align="center" style="font-size: 12pt"><FONT style="font-size: 14pt">Heron Therapeutics Appoints Neil J. Clendeninn, M.D., Ph.D. as Senior Vice President and Chief<BR>
Medical Officer</FONT>



<P align="left" style="font-size: 14pt"><FONT style="font-size: 12pt">REDWOOD CITY, Calif. &#150; October&nbsp;12, 2015 &#150; Heron Therapeutics, Inc. (NASDAQ: HRTX), a
biotechnology company focused on improving the lives of patients by developing best-in-class
medicines that address major unmet medical needs, today announced the appointment of Neil J.
Clendeninn, M.D., Ph.D. as Senior Vice President and Chief Medical Officer. Dr.&nbsp;Clendeninn joins
the Company today and will report to Barry D. Quart, Pharm.D., Chief Executive Officer of Heron.
</FONT>

<P align="left" style="font-size: 12pt">&#147;Neil has been instrumental as an advisor to the Company, specifically in his guidance during our
recently completed MAGIC study for SUSTOL<sup>&#174;</sup> (granisetron)&nbsp;Injection, extended release,
and we are delighted that he will be joining us as a permanent member of our team,&#148; commented Barry
D. Quart, Pharm.D., Chief Executive Officer of Heron. &#147;Neil brings over 30&nbsp;years of experience in
drug development and clinical practice to his role at Heron, and we look forward to his leadership
in all areas of our business as we move forward in our goals of developing best-in-class medicines
with the potential to improve the lives of patients suffering from cancer or pain.&#148;


<P align="left" style="font-size: 12pt">Since 2001, Dr.&nbsp;Clendeninn has been the president of CANAID, Inc. his own consultancy firm, and
prior to joining Heron, he was an advisor to the Company in that capacity. Additionally, Dr.
Clendeninn is currently a practicing physician and serves as Program Director for Palliative
Medicine Partners: Complex Illness Coordination, a program of Kauai Hospice in Kauai, Hawaii. From
1993 until 2001, Dr.&nbsp;Clendeninn served as Senior Vice President and Head of Clinical Affairs at
Agouron Inc. Prior to this, beginning in 1985, he was Director of the Clinical Oncology Department
at Burroughs-Welcome Company. Simultaneous to these roles, Dr.&nbsp;Clendeninn served as a practicing
physician and held academic faculty roles at various institutions, among them, the University of
North Carolina at Chapel Hill and the National Cancer Institute at the National Institutes of
Health in Rockville, MD. In addition, Dr.&nbsp;Clendeninn currently sits on several Boards, including
the Board of Directors at OncoGenex Pharmaceuticals in Bothell, WA, and is a Scientific Medical
Advisor at the Cancer Prevention & Research Initiative of Texas. Previously, he served on the Board
of Scientific Advisors at the National Cancer Institute of the National Institutes of Health, from
2001 through 2005. He received an M.D. and Ph.D. degree in microbiology and pharmacology from New
York University in New York, NY.


<P align="left" style="font-size: 12pt"><B>About Heron Therapeutics, Inc.</B>


<P align="left" style="font-size: 12pt">Heron Therapeutics, Inc. is a biotechnology company focused on improving the lives of patients by
developing best-in-class medicines that address major unmet medical needs. Heron is developing
novel, patient-focused solutions that apply its innovative science and technologies to
already-approved pharmacological agents. Heron&#146;s goal is to build on therapeutics with well-known
pharmacology by improving their tolerability and efficacy as well as broadening their potential
field of use. Heron is currently developing four pharmaceutical products for patients suffering
from cancer or pain. SUSTOL<sup>&#174;</sup> (granisetron)&nbsp;Injection, extended release is being
developed for the prevention of both acute and delayed chemotherapy-induced nausea and vomiting
(CINV)&nbsp;associated with moderately emetogenic chemotherapy (MEC)&nbsp;or highly emetogenic chemotherapy
(HEC). CINV is one of the most debilitating side effects of chemotherapy and is a leading cause of
premature discontinuation of cancer treatment. Heron recently reported positive, top-line results
from its Phase 3 MAGIC study. In July&nbsp;2015, Heron resubmitted its New Drug Application (NDA)&nbsp;for
SUSTOL to the U.S. Food and Drug Administration (FDA), and the FDA has assigned a Prescription Drug
User Fee Act (PDUFA)&nbsp;goal date of January&nbsp;17, 2016. HTX-019, also being developed for the
prevention of CINV, has the potential to become the first polysorbate 80-free, intravenous
formulation of aprepitant, a neurokinin-1 (NK<sub>1</sub>) receptor antagonist. Heron intends to
file an NDA for HTX-019 using the 505(b)(2) regulatory pathway in the second half of 2016. HTX-011
is Heron&#146;s long-acting formulation of the local anesthetic bupivacaine in a fixed-dose combination
with the anti-inflammatory meloxicam. In September&nbsp;2015, Heron reported positive, top-line results
from a Phase 2 study of HTX-011 in patients undergoing bunionectomy. In this study, HTX-011
significantly reduced pain intensity and the need for opioid rescue medications. HTX-011 is the
subject of a broad-based development program designed to target the many patients undergoing a wide
range of surgeries who experience significant post-operative pain. HTX-003, a long-acting
formulation of buprenorphine, is being developed for the potential management of chronic pain and
opioid addiction. All of Heron&#146;s product candidates utilize Heron&#146;s innovative science and
technology platforms, including its proprietary Biochronomer<sup>&#174;</sup> drug delivery technology,
which can deliver therapeutic levels of a wide range of otherwise short-acting pharmacological
agents over a period of days to weeks with a single injection.


<P align="left" style="font-size: 12pt">For more information, please visit <U>www.herontx.com</U>.


<P align="left" style="font-size: 12pt"><B>Forward Looking Statements</B>


<P align="left" style="font-size: 12pt">This news release contains &#147;forward-looking statements&#148; as defined by the Private Securities
Litigation Reform Act of 1995. Heron cautions readers that forward-looking statements are based on
management&#146;s expectations and assumptions as of the date of this news release and are subject to
certain risks and uncertainties that could cause actual results to differ materially. These risks
and uncertainties include, but are not limited to, those associated with: whether the U.S. Food and
Drug Administration (FDA)&nbsp;approves the SUSTOL NDA as submitted or supports as broad of a labeled
indication for SUSTOL as requested, the progress in the research and development of HTX-019,
HTX-011, HTX-003 and our other programs, including the timing of preclinical, clinical, and
manufacturing activities, safety and efficacy results from our studies that may not justify the
pursuit of further development of our product candidates, the launch and acceptance of SUSTOL and
new products generally, our financial position and our ability to raise additional capital to fund
operations, if necessary, or to pursue additional business opportunities, strategic business
alliances we may pursue or the potential acquisition of products or technologies, and our ability
to grow our organization to sustain the commercial launch for SUSTOL, and other risks and
uncertainties identified in the Company&#146;s filings with the Securities and Exchange Commission.
Forward-looking statements reflect our analysis only on their stated date, and Heron takes no
obligation to update or revise these statements except as may be required by law.


<P align="left" style="font-size: 12pt"><B>Contacts:</B>
<BR>
<B>Investor Relations Contact:</B>
<BR>
Jennifer Capuzelo, Associate Director, Investor Relations
<BR>
858-703-6063
<BR>
<U>jcapuzelo@herontx.com</U>


<P align="left" style="font-size: 12pt"><B>Corporate Contact:</B>
<BR>
Barry D. Quart, Pharm D., Chief Executive Officer
<BR>
650-366-2626


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