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Note 4 - Balance Sheet Details | 12 Months Ended
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Dec. 31, 2015
Notes to Financial Statements |
Supplemental Balance Sheet Disclosures [Text Block] |
4. | Balance Sheet Details
Short-Term Investments The following is a summary of our short-term, available-for-sale securities (in thousands):
|  | December 31, 201 5 |
|  |  |  |  |  | Gross |  |  | Gross |  |  |  |  |
|  | Amortized |  |  | Unrealized |  |  | Unrealized |  |  | Estimated |
|  | Cost |  |  | Gains |  |  | Losses |  |  | Fair Value |
United States corporate debt |  | $ | 28,750 |  |  | $ | — |  |  | $ | (35 | ) |  | $ | 28,715 |
Foreign corporate debt |  |  | 4,927 |  |  |  | — |  |  |  | (5 | ) |  |  | 4,922 |
United States commercial paper |  |  | 7,770 |  |  |  | — |  |  |  | — |  |  |  | 7,770 |
Foreign commercial paper |  |  | 15,579 |  |  |  | — |  |  |  | — |  |  |  | 15,579 |
Total |  | $ | 57,026 |  |  | $ | — |  |  | $ | (40 | ) |  | $ | 56,986 |
The amortized cost of debt securities is adjusted for amortization of premiums and accretion of discounts to maturity. We regularly monitor and evaluate the realizable value of our marketable securities. We did not recognize any impairment losses for the year ended December 31, 2015. Property and Equipment Property and equipment is comprised of the following (in thousands):
|  | December 31, |
|  | 2015 |  |  | 2014 |
Scientific equipment |  | $ | 5,593 |  |  | $ | 4,793 |
Computer equipment and software |  |  | 1,272 |  |  |  | 1,133 |
Furniture, fixtures and office equipment |  |  | 352 |  |  |  | 351 |
Leasehold improvements |  |  | 1,384 |  |  |  | 1,376 |
|  |  | 8,601 |  |  |  | 7,653 |
Less: accumulated depreciation and amortization |  |  | (5,552 | ) |  |  | (4,833 | )
|  | $ | 3,049 |  |  | $ | 2,820 |
Depreciation and amortization expense for the years ended December 31, 2015, 2014 and 2013 was approximately $734,000, $578,000 and $333,000, respectively. During the year ended December 31, 2014, we recognized $905,000 as an impairment loss due to the write-down of a piece of manufacturing-related equipment. As of December 31, 2014, the estimated fair value of the equipment was approximately $115,000. In 2015, we sold the equipment for cash proceeds of $241,000. Accrued Payroll and Employee Liabilities and Other Accrued Expense Accrued payroll and employee liabilities and other accrued expense consisted of the following (in thousands):
|  | December 31, |
|  | 20 15 |  |  | 2014 |
Accrued employee salaries and benefits |  | $ | 1,863 |  |  | $ | 719 |
Accrued bonuses |  |  | 2,965 |  |  |  | 2,012 |
Total accrued payroll and employee liabilities |  | $ | 4,828 |  |  | $ | 2,731 |
|  | December 31, |
|  | 2015 |  |  | 2014 |
Accrued consulting and professional fees |  | $ | 3,914 |  |  | $ | 1,775 |
Accrued accounts payable |  |  | 36 |  |  |  | 886 |
Deferred rent |  |  | 61 |  |  |  | 105 |
Other accrued liabilities |  |  | 143 |  |  |  | 165 |
Total other accrued expense |  | $ | 4,154 |  |  | $ | 2,931 |

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