XML 35 R22.htm IDEA: XBRL DOCUMENT v3.3.1.900

Note 7 - Stockholders' Equity (Tables)

12 Months Ended

Dec. 31, 2015

Notes Tables

Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]

		Number of Shares Outstanding				Exercise Price			Expiration Date
Issued to private placement investors in July 2011			2,965,477			$	3.60		07/01/2016
Issued in a public offering in June 2014			600,000			$	0.01		06/30/2021
Total warrants outstanding			3,565,477

Common Stock Reserved for Future Issuance [Table Text Block]

		Number of Shares
Stock options outstanding			8,434,988
Stock options available for grant			3,880,849
Employee stock purchase plan			99,532
Warrants outstanding			3,565,477
Common stock underlying Convertible Notes outstanding			7,086,560
Total shares reserved for future issuance			23,067,406

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

		Outstanding Options
						Weighted-
						Average
		Number of				Exercise
		Shares				Price
Balance at December 31, 2012			4,323,874			$	8.46
Granted			4,256,971				8.08
Exercised			(537,029	)			5.20
Cancelled			(1,688,135	)			9.45
Balance at December 31, 2013			6,355,681				8.22
Granted			3,181,001				9.40
Exercised			(756,593	)			6.34
Cancelled			(862,085	)			9.88
Balance at December 31, 2014			7,918,004				8.69
Granted			2,134,505				28.95
Exercised			(1,042,343	)			9.15
Cancelled			(575,178	)			10.42
Balance at December 31, 2015			8,434,988			$	13.64

Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding and Exercisable [Table Text Block]

		Years Ended December 31,
		2015								2014								2013
						Weighted-								Weighted-								Weighted-
						Average								Average								Average
						Exercise								Exercise								Exercise
		Options				Price				Options				Price				Options				Price
Exercisable at end of year			2,587,392			$	8.72				2,237,901			$	9.01				1,770,597			$	8.67
Options vested or expected to vest			8,059,481			$	13.38				7,841,074			$	8.69				6,292,296			$	8.22

Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block]

																							Weighted-
											Weighted-												Average
											Average				Weighted-								Exercise
											Remaining				Average								Price of
	Options				Range of						Contractual				Exercise				Options				Options
	Outstanding				Exercise Prices						Life (in years)				Price				Exercisable				Exercisable
		702,903				$3.80	–	$7.00				6.31			$	5.92				466,373			$	5.38
		2,302,688					$7.20					7.33				7.20				711,687				7.20
		2,047,712				$7.61	–	$9.05				8.30				8.91				711,561				8.84
		1,702,732				$9.20	–	$28.30				7.23				14.89				692,974				12.17
		1,678,953				$28.73	–	$128.00				9.71				30.23				4,797				42.60
		8,434,988				$3.80	–	$128.00				7.94				13.64				2,587,392				8.72

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

		December 31,
		2015				2014				2013
Research and development		$	4,701			$	3,329			$	2,562
General and administrative			9,659				4,738				8,328
Stock-based compensation expense included in operating expenses		$	14,360			$	8,067			$	10,890

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

		December 31,
		2015				2014				2013
Risk-free interest rate			1.7	%			1.9	%			1.1	%
Dividend yield			—	%			—	%			—	%
Volatility			92.7	%			99.0	%			104.2	%
Expected life (years)			6				6				6

		December 31,
		2015				2014				2013
Risk-free interest rate			0.1	%			0.1	%			0.1	%
Dividend yield			—	%			—	%			—	%
Volatility			86.7	%			53.8	%			76.0	%
Expected life (months)			6				6				6

X

- Definition

Tabular disclosure of common stock reserved for future issuance.

+ References

No definition available.

+ Details

Name:	hrtx_CommonStockReservedForFutureIssuanceTableTextBlock
Namespace Prefix:	hrtx_
Data Type:	nonnum:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB TOPIC 14.F)
-URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Staff Accounting Bulletin (SAB)
-Number Topic 14
-Section F

+ Details

Name:	us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock
Namespace Prefix:	us-gaap_
Data Type:	nonnum:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of option exercise prices, by grouped ranges, including the upper and lower limits of the price range, the number of shares under option, weighted average exercise price and remaining contractual option terms.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

+ Details

Name:	us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTextBlock
Namespace Prefix:	us-gaap_
Data Type:	nonnum:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(1)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

+ Details

Name:	us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	nonnum:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (f)(2)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

+ Details

Name:	us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	nonnum:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08.(i))
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 50
-Section S99
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6784392&loc=d3e188667-122775

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 505
-SubTopic 50
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=51659978&loc=d3e25284-112666

Reference 5: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Regulation S-X (SX)
-Number 210
-Section 02
-Paragraph 28
-Article 5

+ Details

Name:	us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock
Namespace Prefix:	us-gaap_
Data Type:	nonnum:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Tabular disclosure of the number of fully vested share options (or share units) and share options expected to vest at the date of the latest statement of financial position, weighted-average exercise price (or conversion ratio), aggregate intrinsic value (except for nonpublic entities), and weighted-average remaining contractual term for both options (or share units) currently outstanding and options (or share units) exercisable (or convertible).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (e)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

+ Details

Name:	us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAndExercisableTableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	nonnum:textBlockItemType
Balance Type:	na
Period Type:	duration

X

- References

No definition available.

+ Details

Name:	us-gaap_TableTextBlock
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration