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Note 8 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Notes Tables

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

		December 31,
		201 5				201 4
Deferred tax assets:
Net operating loss carryforward		$	94,465			$	59,513
Research and development credits			11,181				7,667
Stock-based compensation			6,726				5,128
Other, net			1,345				964
Total deferred tax assets			113,717				73,272
Valuation allowance for net deferred tax assets			(113,717	)			(73,272	)
Net deferred taxes		$	—			$	—

Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]

		December 31,
		2015				2014				2013
Statutory federal income tax rate of 34%		$	(33,181	)		$	(25,965	)		$	(18,796	)
Stock-based compensation expense			894				551				513
NOL not benefitted			31,935				25,085				17,983
Other, net			352				329				300
Provision for taxes		$	—			$	—			$	—

X

- Definition

Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 9
-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32639-109319

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X

- Definition

Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 2
-URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32537-109319

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