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Note 7 - Option Summary (Details) - $ / shares
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Number of shares outstanding (in shares) 7,918,004 6,355,681 4,323,874
Number of shares outstanding, weighted average exercise price (in dollars per share) $ 8.69 $ 8.22 $ 8.46
Number of shares granted (in shares) 2,134,505 3,181,001 4,256,971
Number of shares granted, weighted average exercise price (in dollars per share) $ 28.95 $ 9.40 $ 8.08
Number of shares exercised (in shares) (1,042,343) (756,593) (537,029)
Number of shares cancelled (in shares) (575,178) (862,085) (1,688,135)
Number of shares cancelled, weighted average exercise price (in dollars per share) $ 10.42 $ 9.88 $ 9.45
Number of shares outstanding (in shares) 8,434,988 7,918,004 6,355,681
Number of shares outstanding, weighted average exercise price (in dollars per share) $ 13.64 $ 8.69 $ 8.22
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price $ 9.15 $ 6.34