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Note 7 - Stockholders' Equity - Allocation of the Recognized Cost (Details) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2016 | Sep. 30, 2015 | Sep. 30, 2016 | Sep. 30, 2015
Research and Development Expense [Member] |  |  |  |
Share-based compensation expense | $ 3,946 | $ 927 | $ 8,347 | $ 2,652
General and Administrative Expense [Member] |  |  |  |
Share-based compensation expense | 1,763 | 1,068 | 5,229 | 3,540
Selling and Marketing Expense [Member] |  |  |  |
Share-based compensation expense | 1,802 | 826 | 5,121 | 2,320
Share-based compensation expense | $ 7,511 | $ 2,821 | $ 18,697 | $ 8,512
Impact on basic and diluted net loss per share (in dollars per share) | $ 0.19 | $ 0.08 | $ 0.50 | $ 0.27

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