<SEC-DOCUMENT>0000812295-16-000107-index.html : 20160510
<SEC-HEADER>0000812295-16-000107.hdr.sgml : 20160510
<ACCEPTANCE-DATETIME>20160510134319
ACCESSION NUMBER:		0000812295-16-000107
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20160510
DATE AS OF CHANGE:		20160510

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HERON THERAPEUTICS, INC. /DE/
		CENTRAL INDEX KEY:			0000818033
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				942875566
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-39444
		FILM NUMBER:		161634982

	BUSINESS ADDRESS:	
		STREET 1:		123 SAGINAW DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063
		BUSINESS PHONE:		6503662626

	MAIL ADDRESS:	
		STREET 1:		123 SAGINAW DRIVE
		STREET 2:		123 SAGINAW DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AP PHARMA INC /DE/
		DATE OF NAME CHANGE:	20010511

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ADVANCED POLYMER SYSTEMS INC /DE/
		DATE OF NAME CHANGE:	19920703

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			JANUS CAPITAL MANAGEMENT LLC
		CENTRAL INDEX KEY:			0000812295
		STANDARD INDUSTRIAL CLASSIFICATION:	UNKNOWN SIC - 0000 [0000]
		IRS NUMBER:				753019302
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		151 DETROIT ST.
		CITY:			DENVER
		STATE:			CO
		ZIP:			80206-4805
		BUSINESS PHONE:		3033333863

	MAIL ADDRESS:	
		STREET 1:		151 DETROIT ST.
		CITY:			DENVER
		STATE:			CO
		ZIP:			80206-4805

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JANUS CAPITAL GROUP INC
		DATE OF NAME CHANGE:	20030103

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JANUS CAPITAL MANAGEMENT LLC
		DATE OF NAME CHANGE:	20020424

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	JANUS CAPITAL CORP
		DATE OF NAME CHANGE:	19931213
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>hrtx5102016.txt
<DESCRIPTION>HRTX 13G/A
<TEXT>
Document 1 - file: hrtx5102016.txt

</DOCUMENT>
</SEC-DOCUMENT>