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Note 4 - Balance Sheet Details | 12 Months Ended
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Dec. 31, 2016
Notes to Financial Statements |
Supplemental Balance Sheet Disclosures [Text Block] |
4. | Balance Sheet Details
Short-Term Investments The following is a summary of our short-term, available-for-sale securities (in thousands):
|  | December 31, 201 6 |
|  |  |  |  |  | Gross |  |  | Gross |  |  |  |  |
|  | Amortized |  |  | Unrealized |  |  | Unrealized |  |  | Estimated |
|  | Cost |  |  | Gains |  |  | Losses |  |  | Fair Value |
United States corporate debt |  | $ | 12,048 |  |  | $ | — |  |  | $ | (9 | ) |  | $ | 12,039 |
Foreign corporate debt |  |  | 14,065 |  |  |  | — |  |  |  | (8 | ) |  |  | 14,057 |
United States commercial paper |  |  | 8,635 |  |  |  | — |  |  |  | — |  |  |  | 8,635 |
Foreign commercial paper |  |  | 2,993 |  |  |  | — |  |  |  | — |  |  |  | 2,993 |
Total |  | $ | 37,741 |  |  | $ | — |  |  | $ | (17 | ) |  | $ | 37,724 |
|  | December 31, 201 5 |
|  |  |  |  |  | Gross |  |  | Gross |  |  |  |  |
|  | Amortized |  |  | Unrealized |  |  | Unrealized |  |  | Estimated |
|  | Cost |  |  | Gains |  |  | Losses |  |  | Fair Value |
United States corporate debt |  | $ | 27,750 |  |  | $ | — |  |  | $ | (35 | ) |  | $ | 27,715 |
Foreign corporate debt |  |  | 4,927 |  |  |  | — |  |  |  | (5 | ) |  |  | 4,922 |
United States commercial paper |  |  | 7,770 |  |  |  | — |  |  |  | — |  |  |  | 7,770 |
Foreign commercial paper |  |  | 15,579 |  |  |  | — |  |  |  | — |  |  |  | 15,579 |
Total |  | $ | 56,026 |  |  | $ | — |  |  | $ | (40 | ) |  | $ | 55,986 |
The amortized cost of debt securities is adjusted for amortization of premiums and accretion of discounts to maturity. We regularly monitor and evaluate the realizable value of our marketable securities. We did not recognize any impairment losses for the years ended December 31, 2016 and 2015. Inventory Inventory consists of the following (in thousands):
|  | December 31, |
|  | 2016 |  |  | 2015 |
Raw materials |  | $ | 1,647 |  |  | $ | — |
Work in process |  |  | 1,104 |  |  |  | — |
Finished goods |  |  | 2,589 |  |  |  | — |
Total inventory |  | $ | 5,340 |  |  | $ | — |
Property and Equipment Property and equipment consists of the following (in thousands):
|  | December 31, |
|  | 2016 |  |  | 2015 |
Scientific equipment |  | $ | 7,952 |  |  | $ | 5,593 |
Computer equipment and software |  |  | 1,429 |  |  |  | 1,272 |
Furniture, fixtures and office equipment |  |  | 674 |  |  |  | 352 |
Leasehold improvements |  |  | 1,635 |  |  |  | 1,384 |
Property and equipment |  |  | 11,690 |  |  |  | 8,601 |
Less: accumulated depreciation and amortization |  |  | (6,614 | ) |  |  | (5,552 | )
Property and equipment, net |  | $ | 5,076 |  |  | $ | 3,049 |
Depreciation and amortization expense for the years ended December 31, 2016, 2015 and 2014 was $1.1 million, $0.7 million and $0.6 million, respectively. As of December 31, 2016 and 2015, $1.7 million and $0.2 million of property and equipment, respectively, were in process and not depreciated during the respective years. During the year ended December 31, 2014, we recognized $0.9 million as an impairment loss due to the write-down of a piece of manufacturing-related equipment. In 2015, we sold the equipment for cash proceeds of $0.2 million, with a net gain of $0.1 million. Accrued Payroll and Employee Liabilities and Other Accrued Liabilities Accrued payroll and employee liabilities consist of the following (in thousands):
|  | December 31, |
|  | 20 16 |  |  | 2015 |
Accrued employee salaries and benefits |  | $ | 2,236 |  |  | $ | 1,863 |
Accrued bonuses |  |  | 3,474 |  |  |  | 2,965 |
Accrued expenses for realignment (see Note 6) |  |  | 2,704 |  |  |  | — |
Total accrued payroll and employee liabilities |  | $ | 8,414 |  |  | $ | 4,828 |
Other accrued liabilities consist of the following (in thousands):
|  | December 31, |
|  | 2016 |  |  | 2015 |
Accrued consulting and professional fees |  | $ | 4,703 |  |  | $ | 3,914 |
Accrued accounts payable |  |  | 1,039 |  |  |  | 36 |
Accrued sales allowances |  |  | 342 |  |  |  | — |
Deferred rent |  |  | 116 |  |  |  | 61 |
Other accrued liabilities |  |  | 88 |  |  |  | 143 |
Total other accrued liabilities |  | $ | 6,288 |  |  | $ | 4,154 |

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