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Note 9 - Income Taxes - Components of Deferred Tax Assets (Details) - USD ($) $ in Thousands | Dec. 31, 2016 | Dec. 31, 2015
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carryforward | $ 138,727 | $ 94,465
Research and development credits | 16,687 | 11,181
Stock-based compensation | 10,272 | 6,726
Other, net | 3,204 | 1,345
Total deferred tax assets | 168,890 | 113,717
Valuation allowance for net deferred tax assets | (168,890) | (113,717)
Net deferred taxes |  |

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