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Note 11 - Summary of Quarterly Consolidated Financial Data (unaudited) | 12 Months Ended
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Dec. 31, 2016
Notes to Financial Statements |
Quarterly Financial Information [Text Block] |
11 . | Summary of Quarterly Consolidated Financial Data (unaudited)
The following is a summary of the unaudited quarterly results of operations for the years ended December 31, 2016 and 2015:
|  | 2016 |
|  | First Quarter |  |  | Second Quarter |  |  | Third Quarter |  |  | Fourth Quarter |
|  | (In thousands, except per share amounts) |
Revenues: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net product sales |  | $ | — |  |  | $ | — |  |  | $ | — |  |  | $ | 1,279 |
Operating expenses: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cost of product sales |  |  | — |  |  |  | — |  |  |  | — |  |  |  | 35 |
Research and development |  |  | 16,092 |  |  |  | 27,286 |  |  |  | 30,242 |  |  |  | 29,505 |
General and administrative |  |  | 5,367 |  |  |  | 4,774 |  |  |  | 5,333 |  |  |  | 5,892 |
Sales and marketing |  |  | 11,853 |  |  |  | 11,006 |  |  |  | 12,159 |  |  |  | 12,650 |
Loss from operations |  |  | (33,312 | ) |  |  | (43,066 | ) |  |  | (47,734 | ) |  |  | (46,803 | )
Interest income |  |  | 118 |  |  |  | 97 |  |  |  | 111 |  |  |  | 119 |
Interest expense |  |  | (251 | ) |  |  | (257 | ) |  |  | (886 | ) |  |  | (1,270 | )
Other expense |  |  | — |  |  |  | — |  |  |  | — |  |  |  | (9 | )
Net loss |  | $ | (33,445 | ) |  | $ | (43,226 | ) |  | $ | (48,509 | ) |  | $ | (47,963 | )
Basic and diluted net loss per share |  | $ | (0.92 | ) |  | $ | (1.17 | ) |  | $ | (1.24 | ) |  | $ | (1.22 | )
|  | 2015 |
|  | First Quarter |  |  | Second Quarter |  |  | Third Quarter |  |  | Fourth Quarter |
|  | (In thousands, except per share amounts) |
Operating expenses: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  | $ | 14,504 |  |  | $ | 16,175 |  |  | $ | 14,241 |  |  | $ | 16,263 |
General and administrative |  |  | 3,587 |  |  |  | 4,082 |  |  |  | 4,127 |  |  |  | 6,599 |
Sales and marketing |  |  | 2,269 |  |  |  | 2,757 |  |  |  | 4,123 |  |  |  | 8,198 |
Loss from operations |  |  | (20,360 | ) |  |  | (23,014 | ) |  |  | (22,491 | ) |  |  | (31,060 | )
Interest income |  |  | 22 |  |  |  | 26 |  |  |  | 61 |  |  |  | 65 |
Interest expense |  |  | (232 | ) |  |  | (237 | ) |  |  | (242 | ) |  |  | (247 | )
Other income |  |  | — |  |  |  | 118 |  |  |  | — |  |  |  | — |
Net loss |  | $ | (20,570 | ) |  | $ | (23,107 | ) |  | $ | (22,672 | ) |  | $ | (31,242 | )
Basic and diluted net loss per share |  | $ | (0.70 | ) |  | $ | (0.74 | ) |  | $ | (0.63 | ) |  | $ | (0.87 | )

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- Definition The entire disclosure for quarterly financial data. Includes, but is not limited to, tabular presentation of financial information for fiscal quarters, effect of year-end adjustments, and an explanation of matters or transactions that affect comparability of the information. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=68076893&loc=d3e1570-108306 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=68064558&loc=d3e765-108305 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 45 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=68064558&loc=d3e725-108305 + Details
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