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Note 8 - Stockholders' Equity - Exercise Price Range (Details) | 12 Months Ended
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Dec. 31, 2016 $ / shares shares
Options Outstanding (in shares) | shares | 11,845,376
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 3.80
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 102.40
Weighted-Average Remaining Contractual Life (Year) | 7 years 219 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 14.44
Options Exercisable (in shares) | shares | 4,356,665
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 11.66
Exercise Price Range 1 [Member] |
Options Outstanding (in shares) | shares | 581,518
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 3.80
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 7
Weighted-Average Remaining Contractual Life (Year) | 1 year 3 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 6.02
Options Exercisable (in shares) | shares | 581,518
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 6.02
Exercise Price Range 2 [Member] |
Options Outstanding (in shares) | shares | 1,935,473
Range of Exercise Prices, Lower Limit (in dollars per share) |
Range of Exercise Prices, Upper Limit (in dollars per share) |
Weighted-Average Remaining Contractual Life (Year) | 6 years 102 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 7.20
Options Exercisable (in shares) | shares | 1,054,143
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 7.20
Exercise Price Range 3 [Member] |
Options Outstanding (in shares) | shares | 1,793,013
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 7.61
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 9.05
Weighted-Average Remaining Contractual Life (Year) | 7 years 32 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 8.93
Options Exercisable (in shares) | shares | 1,104,899
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 8.94
Exercise Price Range 4 [Member] |
Options Outstanding (in shares) | shares | 843,387
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 9.20
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 12.65
Weighted-Average Remaining Contractual Life (Year) | 4 years 83 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 10.33
Options Exercisable (in shares) | shares | 736,434
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 10.39
Exercise Price Range 5 [Member] |
Options Outstanding (in shares) | shares | 2,271,111
Range of Exercise Prices, Lower Limit (in dollars per share) |
Range of Exercise Prices, Upper Limit (in dollars per share) |
Weighted-Average Remaining Contractual Life (Year) | 9 years 354 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 13
Options Exercisable (in shares) | shares |
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) |
Exercise Price Range 6 [Member] |
Options Outstanding (in shares) | shares | 548,025
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 13.20
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 16.62
Weighted-Average Remaining Contractual Life (Year) | 7 years 138 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 15.46
Options Exercisable (in shares) | shares | 202,650
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 14.57
Exercise Price Range 7 [Member] |
Options Outstanding (in shares) | shares | 1,241,350
Range of Exercise Prices, Lower Limit (in dollars per share) |
Range of Exercise Prices, Upper Limit (in dollars per share) |
Weighted-Average Remaining Contractual Life (Year) | 9 years 259 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 16.83
Options Exercisable (in shares) | shares | 51,320
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 16.83
Exercise Price Range 8 [Member] |
Options Outstanding (in shares) | shares | 1,226,884
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 17.10
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 28.30
Weighted-Average Remaining Contractual Life (Year) | 8 years 149 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 22.48
Options Exercisable (in shares) | shares | 164,692
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 26.76
Exercise Price Range 9 [Member] |
Options Outstanding (in shares) | shares | 1,203,272
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 28.73
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 29.86
Weighted-Average Remaining Contractual Life (Year) | 8 years 178 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 29.44
Options Exercisable (in shares) | shares | 395,686
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 29.44
Exercise Price Range 10 [Member] |
Options Outstanding (in shares) | shares | 201,343
Range of Exercise Prices, Lower Limit (in dollars per share) | $ 29.95
Range of Exercise Prices, Upper Limit (in dollars per share) | $ 102.40
Weighted-Average Remaining Contractual Life (Year) | 8 years 222 days
Weighted-Average Remaining Exercise Price (in dollars per share) | $ 34.78
Options Exercisable (in shares) | shares | 65,323
Weighted-Average Exercise Price of Options Exercisable (in dollars per share) | $ 35.03

X
- Definition The floor of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (g) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition The number of shares reserved for issuance pertaining to the outstanding exercisable stock options as of the balance sheet date in the customized range of exercise prices for which the market and performance vesting condition has been satisfied. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(iii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition The number of shares reserved for issuance pertaining to the outstanding stock options as of the balance sheet date for all option plans in the customized range of exercise prices. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition The ceiling of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (g) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Weighted average exercise price as of the balance sheet date for those equity-based payment arrangements exercisable and outstanding. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition The weighted average price as of the balance sheet date at which grantees could acquire the underlying shares with respect to all outstanding stock options which are in the customized range of exercise prices. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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