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Note 1 - Organization and Business
12 Months Ended
Dec. 31, 2016
Notes to Financial Statements  
Business Description and Basis of Presentation [Text Block]
1.
Organization and Business
 
Heron Therapeutics, Inc. (the “Company”, “Heron”, or “we”) is a commercial-stage biotechnology company focused on improving the lives of patients by developing best-in-class medicines that address major unmet medical needs. We are developing novel, patient-focused solutions that apply our innovative science and technologies to already-approved pharmacological agents.
 
On
August
9,
2016,
our
first
commercial product, SUSTOL
®
(granisetron) extended-release injection (“SUSTOL”), was approved by the U.S. Food and Drug Administration (“FDA”). SUSTOL is indicated, in combination with other antiemetics, in adults for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide combination chemotherapy regimens. We commenced commercial sales of SUSTOL in
October
2016.
 
 
We have
two
investigational pharmaceutical products for patients suffering from cancer or post-operative pain. CINVANTI™ (
HTX-
019),
an intravenous formulation of the neurokinin-
1
receptor antagonist aprepitant, has been developed for the prevention of chemotherapy-induced nausea and vomiting as an adjunct to other antiemetic agents. HTX-
011,
a long-acting formulation of the local anesthetic bupivacaine in a fixed-dose combination with the anti-inflammatory meloxicam, is being developed for the prevention of post-operative pain.
 
 
We have incurred significant operating losses and negative cash flows from operations. As of
December
31,
2016,
our accumulated deficit was
$586.0
million and we had
$51.1
million in cash, cash equivalents and short-term investments. In
January
2017,
we completed an underwritten public offering of our common stock for net proceeds of
$163.7
million. As of
December
31,
2016,
our pro-forma cash, cash equivalents and short-term investments, adjusting for the
January
2017
public offering, was
$214.8
million. Based on our current operating plan and projections, management believes that available cash, cash equivalents and short-term investments are sufficient to fund operations for at least
one
year from the date this annual report on Form
10
-K is filed with the U.S. Securities and Exchange Commission (the “SEC”).