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Note 3 - Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2017
Notes Tables  
Available-for-sale Securities [Table Text Block]
 
 
March 31, 2017
 
 
 
 
 
 
 
Gross
 
 
Gross
 
 
 
 
 
 
 
Amortized
 
 
Unrealized
 
 
Unrealized
 
 
Estimated
 
 
 
Cost
 
 
Gains
 
 
Losses
 
 
Fair Value
 
United States government and agency
  $
24,971
    $
    $
    $
24,971
 
United States corporate debt
   
35,052
     
     
(29
)
   
35,023
 
Foreign corporate debt
   
8,301
     
     
(1
)
   
8,300
 
United States commercial paper
   
36,897
     
     
     
36,897
 
Foreign commercial paper
   
16,933
     
     
     
16,933
 
Total
  $
122,154
    $
    $
(30
)
  $
122,124
 
 
 
December 31, 2016
 
 
 
 
 
 
 
Gross
 
 
Gross
 
 
 
 
 
 
 
Amortized
 
 
Unrealized
 
 
Unrealized
 
 
Estimated
 
 
 
Cost
 
 
Gains
 
 
Losses
 
 
Fair Value
 
United States corporate debt
  $
12,048
    $
    $
(9
)
  $
12,039
 
Foreign corporate debt
   
14,065
     
     
(8
)
   
14,057
 
United States commercial paper
   
8,635
     
     
     
8,635
 
Foreign commercial paper
   
2,993
     
     
     
2,993
 
Total
  $
37,741
    $
    $
(17
)
  $
37,724
 
Valuation Allowances and Reserves [Table Text Block]
 
 
Product
Returns
 
 
Distributor
Fees
 
 
Rebates and
Chargebacks
 
 
Total
 
                                 
Balance at December 31, 2016
  $
49
    $
72
    $
221
    $
342
 
Provision
   
153
     
215
     
1,114
     
1,482
 
Payments/credits
   
     
(119
)    
(243
)    
(362
)
Balance at March 31, 2017
  $
202
    $
168
    $
1,092
    $
1,462
 
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
 
 
As of March 31,
 
 
 
2017
 
 
2016
 
                 
Stock options outstanding
   
11,849
     
8,961
 
Warrants outstanding
   
625
     
3,565
 
Shares of common stock underlying Convertible Notes outstanding
   
7,634
     
7,193