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Note 3 - Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2017

Notes Tables

Available-for-sale Securities [Table Text Block]

		June 30, 2017
						Gross				Gross
		Amortized				Unrealized				Unrealized				Estimated
		Cost				Gains				Losses				Fair Value
United States government and agency		$	19,983			$	—			$	(2	)		$	19,981
United States corporate debt			12,593				—				(3	)			12,590
United States commercial paper			25,451				—				(1	)			25,450
Foreign commercial paper			25,960				—				—				25,960
Total		$	83,987			$	—			$	(6	)		$	83,981

		December 31, 2016
						Gross				Gross
		Amortized				Unrealized				Unrealized				Estimated
		Cost				Gains				Losses				Fair Value
United States corporate debt		$	12,048			$	—			$	(9	)		$	12,039
Foreign corporate debt			14,065				—				(8	)			14,057
United States commercial paper			8,635				—				—				8,635
Foreign commercial paper			2,993				—				—				2,993
Total		$	37,741			$	—			$	(17	)		$	37,724

Valuation Allowances and Reserves [Table Text Block]

		Product Returns				Distributor Fees				GPO Fees, Rebates and Chargebacks				Total
Balance at December 31, 2016		$	49			$	72			$	221			$	342
Provision			248				744				5,063				6,055
Payments/credits			(1	)			(507	)			(1,557	)			(2,065	)
Balance at June 30, 2017		$	296			$	309			$	3,727			$	4,332

Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]

		As of June 30,
		2017				2016
Stock options outstanding			11,966				8,747
Warrants outstanding			625				600
Shares of common stock underlying Convertible Notes outstanding			7,749				7,301

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