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Note 3 - Accounting Policies (Tables)
9 Months Ended
Sep. 30, 2017
Notes Tables  
Available-for-sale Securities [Table Text Block]
   
September
30, 2017
 
   
 
 
 
 
Gross
   
Gross
   
 
 
 
   
Amortized
   
Unrealized
   
Unrealized
   
Estimated
 
   
Cost
   
Gains
   
Losses
   
Fair Value
 
United States
commercial paper
  $
4,493
    $
    $
    $
4,493
 
Foreign commercial paper
   
3,999
     
     
     
3,999
 
Total
  $
8,492
    $
    $
    $
8,492
 
   
December
31, 2016
 
   
 
 
 
 
Gross
   
Gross
   
 
 
 
   
Amortized
   
Unrealized
   
Unrealized
   
Estimated
 
   
Cost
   
Gains
   
Losses
   
Fair Value
 
United States corporate debt
  $
12,048
    $
    $
(9
)
  $
12,039
 
Foreign corporate debt
   
14,065
     
     
(8
)
   
14,057
 
United States commercial paper
   
8,635
     
     
     
8,635
 
Foreign commercial paper
   
2,993
     
     
     
2,993
 
Total
  $
37,741
    $
    $
(17
)
  $
37,724
 
Valuation Allowances and Reserves [Table Text Block]
   
Product
Returns
   
Distributor
Fees
   
GPO Fees,
Rebates and Chargebacks
   
Total
 
                                 
Balance at December 31, 2016
  $
49
    $
72
    $
221
    $
342
 
Provision
   
291
     
1,328
     
10,049
     
11,668
 
Payments/credits
   
(1
)    
(816
)    
(5,005
)    
(5,822
)
Balance at September
30, 2017
  $
339
    $
584
    $
5,265
    $
6,188
 
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
As of
September
30
,
 
   
2017
   
2016
 
                 
Stock options outstanding
   
11,198
     
8,517
 
Warrants outstanding
   
620
     
600
 
Shares of c
ommon stock underlying Convertible Notes outstanding
   
7,865
     
7,410