XML 35 R23.htm IDEA: XBRL DOCUMENT
v3.8.0.1

Note 8 - Stockholders' Equity (Tables) | 12 Months Ended
--- | ---
Dec. 31, 2017
Notes Tables |
Common Stock Reserved for Future Issuance [Table Text Block] |
|  | Number of Shares |
Stock options outstanding |  |  | 13,462,963 |
Stock options available for grant |  |  | 4,685,432 |
Employee stock purchase plan |  |  | 267,317 |
Warrants outstanding |  |  | 620,164 |
Shares of c ommon stock underlying Convertible Notes outstanding (see Note 7) |  |  | 7,982,957 |
Total shares reserved for future issuance |  |  | 27,018,833 |
Share-based Compensation, Stock Options, Activity [Table Text Block] |
|  | Outstanding Options |
|  | Number of Shares |  |  | Weighted- Average Exercise Price |
Balance at December 31, 2014 |  |  | 7,918,004 |  |  | $ | 8.69 |
Granted |  |  | 2,134,505 |  |  |  | 28.95 |
Exercised |  |  | (1,042,343 | ) |  |  | 9.15 |
Cancelled |  |  | (575,178 | ) |  |  | 10.42 |
Balance at Decemb er 31, 2015 |  |  | 8,434,988 |  |  |  | 13.64 |
Granted |  |  | 4,920,661 |  |  |  | 15.98 |
Exercised |  |  | (798,363 | ) |  |  | 8.37 |
Cancelled |  |  | (711,910 | ) |  |  | 22.43 |
Balance at Decemb er 31, 2016 |  |  | 11,845,376 |  |  |  | 14.44 |
Granted |  |  | 4,300,621 |  |  |  | 16.17 |
Exercised |  |  | (1,350,605 | ) |  |  | 8.49 |
Cancelled |  |  | (1,332,429 | ) |  |  | 20.06 |
Balance at December 31, 2017 |  |  | 13,462,963 |  |  |  | 15.03 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding and Exercisable [Table Text Block] |
|  | Years Ended December 31, |
|  | 2017 |  |  | 2016 |  |  | 2015 |
|  | Options |  |  | Weighted- Average Exercise Price |  |  | Options |  |  | Weighted- Average Exercise Price |  |  | Options |  |  | Weighted- Average Exercise Price |
Exercisable at end of year |  |  | 5,446,586 |  |  | $ | 13.25 |  |  |  | 4,356,665 |  |  | $ | 11.66 |  |  |  | 2,587,392 |  |  | $ | 8.72 |
Options vested or expected to vest |  |  | 12,854,571 |  |  | $ | 14.98 |  |  |  | 11,234,529 |  |  | $ | 14.32 |  |  |  | 8,059,481 |  |  | $ | 13.38 |
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block] |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Weighted- |
|  |  |  |  |  |  |  | Weighted- |  |  |  |  |  |  |  |  |  |  | Average |
|  |  |  |  |  |  |  | Average |  |  | Weighted- |  |  |  |  |  |  | Exercise |
|  |  |  |  |  |  |  | Remaining |  |  | Average |  |  |  |  |  |  | Price of |
Options |  |  | Range of |  |  | Contractual |  |  | Exercise |  |  | Options |  |  | Options |
Outstanding |  |  | Exercise Prices |  |  | Life (in years) |  |  | Price |  |  | Exercisable |  |  | Exercisable |
34,906 |  |  |  | $5.20 |  |  |  |  | 3.04 |  |  | $ | 5.20 |  |  |  | 34,906 |  |  | $ | 5.20 |
1,962,586 |  |  | $6.60 | – | $7.20 |  |  |  | 5.30 |  |  |  | 7.19 |  |  |  | 1,587,586 |  |  |  | 7.18 |
1,894,556 |  |  | $ 8.80 | – | $12.90 |  |  |  | 6.23 |  |  |  | 9.55 |  |  |  | 1,610,345 |  |  |  | 9.54 |
1,895,717 |  |  |  | $13.00 |  |  |  |  | 8.88 |  |  |  | 13.00 |  |  |  | 532,872 |  |  |  | 13.00 |
1,900,182 |  |  | $13.05 | – | $16.30 |  |  |  | 8.90 |  |  |  | 14.95 |  |  |  | 278,933 |  |  |  | 15.12 |
1,029,700 |  |  | $16.35 | – | $16.90 |  |  |  | 8.65 |  |  |  | 16.81 |  |  |  | 342,983 |  |  |  | 16.82 |
4,745,316 |  |  | $17.00 | – | $38.46 |  |  |  | 9.02 |  |  |  | 21.00 |  |  |  | 1,058,961 |  |  |  | 26.73 |
13,462,963 |  |  | $ 5.20 | – | $38.46 |  |  |  | 8.01 |  |  |  | 15.03 |  |  |  | 5,446,586 |  |  |  | 13.25 |
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] |
|  | December 31, |
|  | 2017 |  |  | 2016 |  |  | 2015 |
Research and development |  | $ | 11,312 |  |  | $ | 11,316 |  |  | $ | 4,701 |
General and administrative |  |  | 9,469 |  |  |  | 7,402 |  |  |  | 6,282 |
Sales and marketing |  |  | 9,757 |  |  |  | 7,238 |  |  |  | 3,377 |
Total s tock-based compensation expense |  | $ | 30,538 |  |  | $ | 25,956 |  |  | $ | 14,360 |
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] |
|  | December 31, |
|  | 2017 |  |  | 2016 |  |  | 2015 |
Risk-free interest rate |  |  | 2.1 | % |  |  | 1.7 | % |  |  | 1.7 | %
Dividend yield |  |  | — | % |  |  | — | % |  |  | — | %
Volatility |  |  | 74.0 | % |  |  | 89.1 | % |  |  | 92.7 | %
Expected life (years) |  |  | 6 |  |  |  | 6 |  |  |  | 6 |
|  | December 31, |
|  | 2017 |  |  | 2016 |  |  | 2015 |
Risk-free interest rate |  |  | 1.2 | % |  |  | 0.4 | % |  |  | 0.1 | %
Dividend yield |  |  | — | % |  |  | — | % |  |  | — | %
Volatility |  |  | 50.0 | % |  |  | 68.3 | % |  |  | 86.7 | %
Expecte d life (months) |  |  | 6 |  |  |  | 6 |  |  |  | 6 |

X
- Definition Tabular disclosure of common stock reserved for future issuance. + References No definition available. + Details
Name: | hrtx_CommonStockReservedForFutureIssuanceTableTextBlock
Namespace Prefix: | hrtx_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5047-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 + Details
Name: | us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of option exercise prices, by grouped ranges, including the upper and lower limits of the price range, the number of shares under option, weighted average exercise price and remaining contractual option terms. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ScheduleOfShareBasedCompensationSharesAuthorizedUnderStockOptionPlansByExercisePriceRangeTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of number, weighted-average exercise price or conversion ratio, aggregate intrinsic value, and weighted-average remaining contractual term for outstanding and exercisable options that are fully vested and expected to vest. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=96867065&loc=d3e5070-113901 + Details
Name: | us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAndExercisableTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | nonnum:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_TableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration