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Note 2 - Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2017

Notes Tables

Valuation Allowances and Reserves [Table Text Block]

		Product Returns				Distributor Fees				GPO Fees, Rebates and Chargebacks				Total
Balance at December 31, 2016		$	49			$	72			$	221			$	342
Provision			473				2,027				16,752				19,252
Payments/credits			(1	)			(1,519	)			(8,755	)			(10,275	)
Balance at December 31, 2017		$	521			$	580			$	8,218			$	9,319

Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]

		December 31 ,
		2017				2016				2015
Stock options outstanding			13,463				11,845				8,435
Warrants outstanding			620				600				3,565
Shares of c ommon stock underlying Convertible Notes outstanding			7,983				7,521				7,087

X

- Definition

Tabular disclosure of a schedule of allowance and reserve accounts where the valuation and qualifying accounts are either netted against the cost of an asset (in order to value it at its carrying value) or that reflect a liability established to represent expected future costs.

+ References

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- Definition

Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257

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