XML 37 R25.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 11 - Summary of Quarterly Consolidated Financial Data (Unaudited) (Tables)
 12 Months Ended
Dec. 31, 2017
Notes Tables  
Quarterly Financial Information [Table Text Block]
   
2017
  
   
First
Quarter
    
Second
Quarter
    
Third
Quarter
    
Fourth
Quarter
  
   
(In thousands, except per share amounts)
  
Revenue
s:
                                
Net product sales
   $
3,632
     $
8,510
     $
8,572
     $
10,053
  
Cost of product sales
    
(1,186
)
    
(1,013
)
    
(1,051
)
    
(1,338
)
Gross Profit
    
2,446
      
7,497
      
7,521
      
8,715
  
Operating expenses:
                                
Research and development
    
33,384
      
28,597
      
28,844
      
47,757
  
General and
administrative
    
6,742
      
6,185
      
6,462
      
6,165
  
Sales and marketing
    
11,619
      
14,770
      
13,529
      
16,683
  
Loss from operations
    
(49,299
)
    
(42,055
)
    
(41,314
)
    
(61,890
)
Other
expense, net
    
(1,030
)
    
(744
)
    
(552
)
    
(600
)
Net
loss
   $
(50,329
)
   $
(42,799
)
   $
(41,866
)
   $
(62,490
)
Basic
and diluted net loss per share
   $
(1.00
)
   $
(0.80
)
   $
(0.77
)
   $
(1.09
)
   
2016
  
   
First
Quarter
    
Second
Quarter
    
Third
Quarter
    
Fourth
Quarter
  
   
(In thousands, except per share amounts)
  
Revenues:
                                
Net product sales
   $
—
     $
—
     $
—
     $
1,279
  
Cost of product
sales
    
—
      
—
      
—
      
(35
)
Gross Profit
    
—
      
—
      
—
      
1,244
  
Operating e
xpenses:
                                
Research and development
    
16,092
      
27,286
      
30,242
      
29,505
  
General and administrative
    
5,367
      
4,774
      
5,333
      
5,892
  
Sales and marketing
    
11,853
      
11,006
      
12,159
      
12,650
  
Loss from operations
    
(33,312
)
    
(43,066
)
    
(47,734
)
    
(46,803
)
Other
expense, net
    
(133
)
    
(160
)
    
(775
)
    
(1,160
)
Net
loss
   $
(33,445
)
   $
(43,226
)
   $
(48,509
)
   $
(47,963
)
Basic
and diluted net loss per share
   $
(0.92
)
   $
(1.17
)
   $
(1.24
)
   $
(1.22
)