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Note 9 - Income Taxes - Components of Deferred Tax Assets (Details) - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Deferred tax assets:
Net operating loss carryforward	$ 134,659	$ 138,727
Research and development credits	25,919	16,687
Stock-based compensation	8,633	10,272
Other	2,920	3,204
Total gross deferred tax assets	172,131	168,890
Valuation allowance	(172,131)	(168,890)
Net deferred tax assets

X

- Definition

Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.

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