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Note 3 - Accounting Policies (Details Textual) $ in Thousands		3 Months Ended
	Jan. 01, 2018 USD ($)	Mar. 31, 2018 USD ($)	Mar. 31, 2017 USD ($)	Dec. 31, 2017 USD ($)
Asset Impairment Charges, Total		$ 0	$ 0
Available-for-sale Securities, Gross Realized Gains		0	0
Inventory, Net, Total		19,418		$ 10,108
Inventory, Raw Materials, Net of Reserves		5,000		2,700
Inventory, Work in Process, Net of Reserves		8,100		4,200
Inventory, Finished Goods, Net of Reserves		6,300		3,200
Cost of Goods and Services Sold, Total		3,133	1,186
Revenue from Contract with Customer, Including Assessed Tax		11,567	3,632
SEC Schedule, 12-09, Valuation Allowances and Reserves, Amount, Ending Balance		12,604		9,319
Accounting Standards Update 2014-09 [Member]
Cost of Goods and Services Sold, Total	$ 200
Revenue from Contract with Customer, Including Assessed Tax	2,900
Accounting Standards Update 2014-09 [Member] | Product Sales Allowance [Member]
SEC Schedule, 12-09, Valuation Allowances and Reserves, Amount, Ending Balance	1,100
Retained Earnings [Member] | Accounting Standards Update 2014-09 [Member]
Cumulative Effect of New Accounting Principle in Period of Adoption	$ 1,600
SUSTOL [Member]
Inventory, Net, Total		8,500		7,100
Cost of Goods and Services Sold, Total			$ 1,200
CINVANTI [Member]
Inventory, Net, Total		$ 10,900		$ 3,000
Customer Concentration Risk [Member] | Sales Revenue, Net [Member] | SUSTOL [Member]
Number of Major Customers		2
Customer Concentration Risk [Member] | Sales Revenue, Net [Member] | CINVANTI [Member]
Number of Major Customers		3

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